nsfl1c
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  • Official Full Name
  • NSFL1 (p97) cofactor (p47)
  • Background
  • N-ethylmaleimide-sensitive factor (NSF) and valosin-containing protein (p97) are two ATPases known to be involved in transport vesicle/target membrane fusion and fusions between membrane compartments. A trimer of the protein encoded by this gene binds a hexamer of cytosolic p97 and is required for p97-mediated regrowth of Golgi cisternae from mitotic Golgi fragments. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 8.
  • Synonyms
  • NSFL1C; NSFL1 (p97) cofactor (p47); NSFL1 cofactor p47; dJ776F14.1; p47; SHP1 homolog (S. cerevisiae); UBX domain protein 2C; UBX1; UBXD10; UBXN2C; MGC3347; OTTHUMP00000029972; OTTHUMP00000029974; P47 protein; P97 cofactor p47; SHP1 homolog; UBX domain-containing protein 2C
Cat.#:NSFL1C-302HTag:Myc|DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human NSFL1C Protein, MYC/DDK-tagged
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Cat.#:NSFL1C-1373HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human NSFL1C, His-tagged
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Cat.#:NSFL1C-4092RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat NSFL1C Protein
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Cat.#:NSFL1C-3109RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey NSFL1C Protein, His-tagged
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Cat.#:NSFL1C-2553CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken NSFL1C
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Cat.#:NSFL1C-1822ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish NSFL1C
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Cat.#:NSFL1C-3687HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human NSFL1C 293 Cell Lysate
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Involved Pathway

NSFL1C involved in several pathways and played different roles in them. We selected most pathways NSFL1C participated on our site, such as Protein processing in endoplasmic reticulum, which may be useful for your reference. Also, other proteins which involved in the same pathway with NSFL1C were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Protein processing in endoplasmic reticulum
UBQLN3; UBE2D1; UBQLN2; UBE4B; ERO1LB; MAPK8; HSPA2; BAK1; CCDC102A; NFE2L2

Protein Function

NSFL1C has several biochemical functions, for example, ATPase binding, phospholipid binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NSFL1C itself. We selected most functions NSFL1C had, and list some proteins which have the same functions with NSFL1C. You can find most of the proteins on our site.
Function
Related Protein
Function ATPase binding
Related Protein NHP2L1; SLC26A9; BBC3; DNAJC10; ZNHIT6; ATP6V0A1; Ar; PGR; SDF2L1; ATP6V1G3
Function phospholipid binding
Related Protein SPTB; NUP35; ANXA9; PLA2G4C; ANXA1; SPTBN1; PLA2G2A; ANXA5; APOA5; LPAR3
Function protein binding
Related Protein GPSM3; KRT18; P2RX4; ANKMY2; SEMA4A; OCRL; CATSPERG2; DPYSL4; HYPK; KCNJ6
Function protein phosphatase type 1 regulator activity
Related Protein PHACTR3; PHACTR4B; UBXN2A; PPP1R16A; KCNS1; PPP1R7; PHACTR1; UBXN2B; PPP1R16B; PHACTR3A
Function ubiquitin binding
Related Protein IDE; FAM125A; TOP2A; PER2; NPLOC4; HSPB1; USP5; NSFL1C; UCHL1; BRAP

Interacting Protein

NSFL1C has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NSFL1C here. Most of them are supplied by our site. Hope this information will be useful for your research of NSFL1C.
VCP; HEL-S-70; VCPIP1; DBI; RPL22; SRP14; ANP32A; GSK3B; LIPE; TARDBP; GLMN; PHAX; FAM32A; Insr