ntsr1
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  • Official Full Name
  • neurotensin receptor 1 (high affinity)
  • Background
  • Neurotensin receptor 1 belongs to the large superfamily of G-protein coupled receptors. NTSR1 mediates the multiple functions of neurotensin, such as hypotension, hyperglycemia, hypothermia, antinociception, and regulation of intestinal motility and secretion.
  • Synonyms
  • NTSR1; neurotensin receptor 1 (high affinity); neurotensin receptor type 1; NTR; High affinity levocabastine insensitive neurotensin receptor; NT R 1; NTR1; NTRH; NTRR; NTSR 1; NT-R-1; OTTHUMP00000031500; high-affinity levocabastine-insensitive neurotensin receptor
Cat.#:NTSR1-26HTag:N/A
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human NTSR1 Protein
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Cat.#:NTSR1-296HTag:His
Source (Host):Mammalian CellsSpecies:Human
Product nameRecombinant Human NTSR1
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Cat.#:NTSR1-4527CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken NTSR1
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Cat.#:Kit-1447Tag:N/A
Source (Host):Species:
Product nameNTSR1 CHO-K1 β-Arrestin GPCR Assay Kit
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Cat.#:Kit-1448Tag:N/A
Source (Host):Species:
Product nameNTSR1 Activated GPCR Internalization Assay Kit
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Involved Pathway

NTSR1 involved in several pathways and played different roles in them. We selected most pathways NTSR1 participated on our site, such as Calcium signaling pathway, Neuroactive ligand-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with NTSR1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Calcium signaling pathway
ORAI1B; CALM2B; ATP2B2; TACR2; CACNA1D; SPHK2; PPP3CCA; PLCB1; TNNC1A; PRKCBA
Neuroactive ligand-receptor interaction
TACR3A; GPR35; IL12; AGTR1A; CHRNA10; TAAR12B; TAAR12G; CHRNB3A; ADRB2B; THRA

Protein Function

NTSR1 has several biochemical functions, for example, G-protein coupled neurotensin receptor activity, G-protein coupled receptor activity, protein N-terminus binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NTSR1 itself. We selected most functions NTSR1 had, and list some proteins which have the same functions with NTSR1. You can find most of the proteins on our site.
Function
Related Protein
Function G-protein coupled neurotensin receptor activity
Related Protein NTSR1; NTSR2
Function G-protein coupled receptor activity
Related Protein TAS2R118; TAS2R123; GPR30; MRGPRX3; TAS2R130; OLFCS2; NPFFR2; GPR78; TMTOPSA; OLFR149
Function protein N-terminus binding
Related Protein CSNK2A2; RPA3; TBL1XR1; NFE2; SCT; STX5A; HAX1; SMARCC1; TRAF6; EIF3E
Function protein binding
Related Protein KLF15; PCGF3; DYNLL1; FGFRL1A; SMYD2; PARD3; ZBTB7C; KHDC1B; FAP; PENK
Function protein heterodimerization activity
Related Protein TAS1R2; KCNK3; PPP3CA; CHRNB4; TPD52L1; SOX15; Fzd4; HIST3H2BB; EXT2; ITGB1B
Function protein homodimerization activity
Related Protein FGFR1OP; BCL2A1; PLEKHB1; SEPT12; MTHFD1L; ERBB3; OXA1L; SUMF1; PITX2; SOD1

Interacting Protein

NTSR1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NTSR1 here. Most of them are supplied by our site. Hope this information will be useful for your research of NTSR1.
NTS