OS9

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OS9

Official Full Name osteosarcoma amplified 9, endoplasmic reticulum lectin
Background This gene encodes a protein that is highly expressed in osteosarcomas. This protein binds to the hypoxia-inducible factor 1 (HIF-1), a key regulator of the hypoxic response and angiogenesis, and promotes the degradation of one of its subunits. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Synonyms OS9; osteosarcoma amplified 9, endoplasmic reticulum lectin; OS-9; ERLEC2; protein OS-9; erlectin 2; amplified in osteosarcoma 9; endoplasmic reticulum lectin 2; osteosarcoma amplified 9, endoplasmic reticulum associated protein;
    • Species :
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Tag :
    • GST
    • His
    • T7
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human OS9-2851H Recombinant Human OS9 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Mouse Os9-4605M Recombinant Mouse Os9 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Human OS9-6038H Recombinant Human OS9 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human OS9-1468H Recombinant Human OS9, GST-tagged E.coli GST
    Human OS9-3545HCL Recombinant Human OS9 293 Cell Lysate HEK293 N/A
    Human OS9-8003H Recombinant Human OS9 protein, His & T7-tagged E.coli His/T7
    Mouse OS9-12194M Recombinant Mouse OS9 Protein Mammalian Cell His
    Mouse Os9-8004M Recombinant Mouse Os9 protein, His & T7-tagged E.coli His/T7
    Rat OS9-4204R Recombinant Rat OS9 Protein Mammalian Cell His
    Rat Os9-8005R Recombinant Rat Os9 protein, His & T7-tagged E.coli His/T7
    Rhesus Macaque OS9-3249R Recombinant Rhesus monkey OS9 Protein, His-tagged Mammalian Cell His
    Zebrafish OS9-4456Z Recombinant Zebrafish OS9 Mammalian Cell His

    OS9 involved in several pathways and played different roles in them. We selected most pathways OS9 participated on our site, such as Asparagine N-linked glycosylation, Calnexin/calreticulin cycle, Disease, which may be useful for your reference. Also, other proteins which involved in the same pathway with OS9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Asparagine N-linked glycosylation NAPB; TRAPPC4; TRAPPC3; NSFA; LMAN2L; STT3A; TMED10; CSNK1D; SEC23IP; CNIH3
    Calnexin/calreticulin cycle DERL2; MAN1B1; OS9
    Disease MIB1; AMN; JAG2; HEY2; TRAT1; CCDC167; RPL35; NMT2; FDX1L; DOCK2
    Diseases of signal transduction HDAC5; TTR; RNF43; OPN1MW2; TRIM24; OS9; HEYL; MIB1; TNKS2; LRRFIP1
    ER Quality Control Compartment (ERQC) DERL2; MAN1B1; OS9
    Hedgehog ligand biogenesis SCUBE2; NOTUM; DISP2; OS9; NOTUM1A; DERL2; GPC5A; HHAT
    Hh mutants abrogate ligand secretion OS9; DERL2
    Hh mutants that dont undergo autocatalytic processing are degraded by ERAD OS9; DERL2

    OS9 has several biochemical functions, for example, carbohydrate binding, glycoprotein binding, protease binding. Some of the functions are cooperated with other proteins, some of the functions could acted by OS9 itself. We selected most functions OS9 had, and list some proteins which have the same functions with OS9. You can find most of the proteins on our site.

    Function Related Protein
    carbohydrate binding NOMO3; PKD1L3; CLEC4E; GALNT3; LGALS9; CLEC4M; FREM1; VCAN; REG3B; GALNTL6
    glycoprotein binding PLAT; SDCBP; FOXRED2; SERPINA1; SERPINA1A; LGALS1; ERBB2; CSNK1D; PIP; FBXO17
    protease binding TNFAIP3; CD70; ITGA3; CAST; TTN; SELL; CD28; CST3; PANX1; VWF
    protein binding FRMPD1; ZP3; MAPK15; TTC5; CRYGD; DKK1; PPIA; SGOL1; L3MBTL3; BIN2

    OS9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with OS9 here. Most of them are supplied by our site. Hope this information will be useful for your research of OS9.

    HIF1A; EGLN1; env; CREB3; EGLN3; DYSF; ACVR1B; SNRPD2

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