Recombinant Human OS9 protein, His & T7-tagged

• Cat.No.: OS9-8003H
• Product Overview: Recombinant Human OS9 aa. (Asn466~Phe667 (Accession # Q13438)) fused with N-terminal His & T7 tag was produced in E. coli cells.

Specification

• Description: This gene encodes a protein that is highly expressed in osteosarcomas. This protein binds to the hypoxia-inducible factor 1 (HIF-1), a key regulator of the hypoxic response and angiogenesis, and promotes the degradation of one of its subunits. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
• Source: E. coli
• Species: Human
• Tag: His & T7
• Form: Freeze-dried powder
• Molecular Mass: 31kDa as determined by SDS-PAGE reducing conditions.
• Protein length: Asn466~Phe667 (Accession # Q13438)
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: >95%
• Characteristic: The isoelectric point is 6.3.
• Applications: SDS-PAGE; WB; ELISA; IP
• Stability: The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage Buffer: Supplied as lyophilized form in 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5% trehalose, and preservative.
• Reconstitution: Reconstitute in sterile ddH2O.

Gene Information

• Gene Name: OS9 OS9, endoplasmic reticulum lectin [ Homo sapiens (human) ]
• Official Symbol: OS9
• Synonyms: OS-9; ERLEC2; amplified in osteosarcoma 9; endoplasmic reticulum lectin 2; erlectin 2; osteosarcoma amplified 9, endoplasmic reticulum associated protein; osteosarcoma amplified 9, endoplasmic reticulum lectin; protein OS-9
• Gene ID: 10956
• mRNA Refseq: NM_001017956.2
• Protein Refseq: NP_001017956.1
• UniProt ID: Q13438