|Official Full Name||oncostatin M receptor|
|Background||This gene encodes a member of the type I cytokine receptor family. The encoded protein heterodimerizes with interleukin 6 signal transducer to form the type II oncostatin M receptor and with interleukin 31 receptor A to form the interleukin 31 receptor, and thus transduces oncostatin M and interleukin 31 induced signaling events. Mutations in this gene have been associated with familial primary localized cutaneous amyloidosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.|
|Synonyms||OSMR; oncostatin M receptor; oncostatin-M-specific receptor subunit beta; OSMRB; MGC140467; MGC150626; MGC150627; MGC75127; Oncostatin M specific receptor subunit beta; Oncostatin M-specific receptor, beta; IL-31RB; IL-31R-beta; IL-31R subunit beta; IL-31 receptor subunit beta; interleukin-31 receptor subunit beta; oncostatin-M specific receptor beta subunit; PLCA1|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
OSMR involved in several pathways and played different roles in them. We selected most pathways OSMR participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with OSMR were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Cytokine-cytokine receptor interaction||CXCL3; TNFRSF10A; LTA; TNFRSF8; NGFRB; GH2; VEGFAB; IL2RB; IFNA12; CXCR4B|
|PIK-Akt signaling pathway||PDGFB; TLR2; CRTC2; Fgf15; IFNA12; PPP2CA; CCNE1; FGFR3; COL6A6; FLT1|
|Jak-STAT signaling pathway||Ifna11; HRAS; IL2RGA; STAT4; IL9; PTPN11; IFNA21; IL10RA; GM2002; IL29|
OSMR has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by OSMR itself. We selected most functions OSMR had, and list some proteins which have the same functions with OSMR. You can find most of the proteins on our site.
|growth factor binding||IGFBP2B; HTRA1A; ACVR2B; RHBDF1; FLT4; ACVR1C; FGFBP2; GHRHR; NRP1; NKD2|
|contributes_to oncostatin-M receptor activity||OSMR; LIFR; IL6ST|
OSMR has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with OSMR here. Most of them are supplied by our site. Hope this information will be useful for your research of OSMR.
ERBB2; GAPDH; q5nfj2_fratt; BAG3; Bmpr1a