parp4
Share
  • Official Full Name
  • poly (ADP-ribose) polymerase family, member 4
  • Background
  • This gene encodes poly(ADP-ribosyl)transferase-like 1 protein, which is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. Since this protein is not capable of binding DNA directly, its transferase activity may be activated by other factors such as protein-protein interaction mediated by the extensive carboxyl terminus.
  • Synonyms
  • PARP4; poly (ADP-ribose) polymerase family, member 4; ADP ribosyltransferase (NAD+; poly (ADP ribose) polymerase) like 1 , ADPRTL1; poly [ADP-ribose] polymerase 4; p193; VAULT3; von Willebrand factor A domain containing 5C; VPARP; VWA5C; PARP-related; H5
Cat.#:PARP4-156HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human PARP4 protein, GST-tagged
+Inquiry
Cat.#:PARP4-2162HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PARP4, His-tagged
+Inquiry
Cat.#:PARP4-8198HTag:His|T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PARP4 protein, His & T7-tagged
+Inquiry
Cat.#:PARP4-4049CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken PARP4
+Inquiry

Involved Pathway

PARP4 involved in several pathways and played different roles in them. We selected most pathways PARP4 participated on our site, such as Base excision repair, which may be useful for your reference. Also, other proteins which involved in the same pathway with PARP4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Base excision repair
UNG; HMGB1A; PARP3; nth; PARP2; OGG1; XRCC1; MPG; POLB; TDG

Protein Function

PARP4 has several biochemical functions, for example, DNA binding, NAD+ ADP-ribosyltransferase activity, enzyme binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PARP4 itself. We selected most functions PARP4 had, and list some proteins which have the same functions with PARP4. You can find most of the proteins on our site.
Function
Related Protein
Function DNA binding
Related Protein ZNF12; ZNF497; ZNF69; BBX; SP1; HIST1H4G; INO80; TIGD6; ZFP507; CREM
Function NAD+ ADP-ribosyltransferase activity
Related Protein TNKS2; PARP2; GIG2L; CHAT1; GIG2E; GIG2Q; TIPARP; GIG2I; PARP15; PARP6
Function enzyme binding
Related Protein ATXN10; ERN1; PTPLAD2; PARK7; EGLN1; ZFHX3; DAXX; CNTNAP2; HSPA8; KALRN
Function protein binding
Related Protein PTPRC; MRPS27; POLDIP3; PCSK5; TFIP11; IL18; PJA1; TMEM231; FAM9B; BBOX1

Interacting Protein

PARP4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PARP4 here. Most of them are supplied by our site. Hope this information will be useful for your research of PARP4.
ORF; brrf1_ebvg; CCT6A; SMAD3; purL; flgE; trpE; q81m31_bacan; q81uh3_bacan; cof4; fimD7; flgH2; q9wmx2-pro_0000037548; 2_aha_camp; CLTC; Lgals3bp; SNW1