Recombinant Human PARP4 protein, GST-tagged

• Cat.No.: PARP4-156H
• Product Overview: Recombinant Human PARP4(31 a.a. - 140 a.a.) fused with GST tag at N-terminal was expressed in Wheat Germ.

Specification

• Description: This gene encodes poly(ADP-ribosyl)transferase-like 1 protein, which is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. Since this protein is not capable of binding DNA directly, its transferase activity may be activated by other factors such as protein-protein interaction mediated by the extensive carboxyl terminus.
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Form: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
• Molecular Mass: 37.84 kDa
• Applications: Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.

Gene Information

• Gene Name: PARP4 poly (ADP-ribose) polymerase family, member 4 [ Homo sapiens ]
• Official Symbol: PARP4
• Synonyms: PARP4; poly (ADP-ribose) polymerase family, member 4; ADP ribosyltransferase (NAD+; poly (ADP ribose) polymerase) like 1 , ADPRTL1; poly [ADP-ribose] polymerase 4; p193; VAULT3; von Willebrand factor A domain containing 5C; VPARP; VWA5C; PARP-related; H5 proline-rich; I-alpha-I-related; 193 kDa vault protein; vault protein, 193-kDa; poly(ADP-ribose) synthetase; vault poly(ADP-ribose) polymerase; poly(ADP-ribosyl)transferase-like 1; PARP-related/IalphaI-related H5/proline-rich; ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase)-like 1; PH5P; PARPL; PARP-4; ADPRTL1
• Gene ID: 143
• mRNA Refseq: NM_006437
• Protein Refseq: NP_006428
• MIM: 607519
• UniProt ID: Q9UKK3
• Chromosome Location: 13q11
• Pathway: BER complex, organism-specific biosystem; BER complex, conserved biosystem; Base excision repair, organism-specific biosystem; Base excision repair, conserved biosystem
• Function: DNA binding; NAD+ ADP-ribosyltransferase activity; NAD+ ADP-ribosyltransferase activity; enzyme binding; transferase activity, transferring glycosyl groups