Recombinant Human PARP4, His-tagged

• Cat.No.: PARP4-2162H
• Product Overview: Recombinant Human PARP4 was produced inE. coli.Catalytic domain of human minor vault p193 protein (aa 220-574) is fused at the C-terminus to a His-tag.

Specification

• Cat. No.: PARP4-2162H
• Description: PARP4 encodes poly(ADP-ribosyl)transferase-like 1 protein, which is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. Since this protein is not capable of binding DNA directly, its transferase activity may be activated by other factors such as protein-protein interaction mediated by the extensive carboxyl terminus.
• Source: E. coli.
• Purity: ≥98%.
• Formulation: Liquid. In PBS containing 50% glycerol.
• Concentration: 0.2mg/ml.
• Storage: Store at -20°C.

Gene Information

• Gene Name: PARP4 poly (ADP-ribose) polymerase family, member 4 [ Homo sapiens ]
• Synonyms: PARP4; poly (ADP-ribose) polymerase family, member 4; PH5P; p193; PARPL; VPARP; VWA5C; PARP-4; VAULT3; ADPRTL1; poly [ADP-ribose] polymerase 4; PARP-related; H5 proline-rich; I-alpha-I-related; 193 kDa vault protein; vault protein, 193-kDa; poly(ADP-ribose) synthetase; vault poly(ADP-ribose) polymerase; poly(ADP-ribosyl)transferase-like 1; PARP-related/IalphaI-related H5/proline-rich; von Willebrand factor A domain containing 5C; ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase)-like 1; EC 2.4.2.30;KIAA0177
• Gene ID: 143
• mRNA Refseq: NM_006437
• Protein Refseq: NP_006428
• MIM: 607519
• UniProt ID: Q9UKK3
• Chromosome Location: 13q11
• Pathway: Base excision repair
• Function: DNA binding; NAD+ ADP-ribosyltransferase activity; enzyme binding; protein binding; transferase activity, transferring glycosyl groups