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PCDH12

Official Full Name

protocadherin 12
Overview

This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The encoded protein consists of an extracellular domain containing 6 cadherin repeats, a transmembrane domain and a cytoplasmic tail that differs from those of the classical cadherins. The gene localizes to the region on chromosome 5 where the protocadherin gene clusters reside. The exon organization of this transcript is similar to that of the gene cluster transcripts, notably the first large exon, but no significant sequence homology exists. The function of this cellular adhesion protein is undetermined but mouse protocadherin 12 does not bind catenins and appears to have no affect on cell migration or growth.
Synonyms

PCDH12; protocadherin 12; protocadherin-12; VE cadherin 2; VE-cad-2; VE-cadherin 2; vascular cadherin-2; vascular endothelial cadherin 2; vascular endothelial cadherin-2; VECAD2; VE-cadherin-2;

Type

Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Rat

Source

E.coli
HEK293
HEK293T
Mammalian cells

Tag

GST
His
His (Fc)
Avi
Myc
DDK
Myc|DDK
N
T7|His

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	PCDH12-48H	Recombinant Human PCDH12 protein, T7/His-tagged	E.coli	T7/His		Inquiry
Human	PCDH12-1552H	Recombinant Human PCDH12, GST-tagged	E.coli	GST	838-1187aa	$319 / 25ug
Human	PCDH12-547H	Recombinant Human PCDH12 Protein, MYC/DDK-tagged	HEK293	Myc/DDK		Inquiry
Mouse	Pcdh12-991M	Active Recombinant Mouse Pcdh12 Protein, His-tagged	Mammalian cells	His	Leu18-Ala716	Inquiry
Mouse	Pcdh12-6536M	Recombinant Mouse Pcdh12 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	Pcdh12-6536M-B	Recombinant Mouse Pcdh12 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Mouse	Pcdh12-1903M	Recombinant Mouse Pcdh12 Protein, His-tagged	E.coli	N-His	Leu18-Asp272	Inquiry
Mouse	Pcdh12-4702M	Recombinant Mouse Pcdh12 Protein, Myc/DDK-tagged	HEK293T	Myc/DDK		Inquiry
Rat	Pcdh12-1904R	Recombinant Rat Pcdh12 Protein, His-tagged	E.coli	N-His	Leu17-Tyr216	Inquiry

Involved Pathway
Protein Function
Interacting Protein
PCDH12 Related Research Area

PCDH12 involved in several pathways and played different roles in them. We selected most pathways PCDH12 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with PCDH12 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

PCDH12 has several biochemical functions, for example, calcium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PCDH12 itself. We selected most functions PCDH12 had, and list some proteins which have the same functions with PCDH12. You can find most of the proteins on our site.

Function	Related Protein
calcium ion binding	NOTCH2NL;CDH1;DUOX2;PROS1;THBS4A;CDH2;MMP14A;BMP1A;PLCD1

PCDH12 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PCDH12 here. Most of them are supplied by our site. Hope this information will be useful for your research of PCDH12.

BALF4 (provisional); MYBPC2

Calcium-binding Proteins and Related Molecules

Cadherin Superfamily