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PCGF1

  • Official Full Name

    polycomb group ring finger 1

  • Overview

    PCGF1 is a mammalian homolog of the Drosophila polycomb group genes, which act as transcriptional repressors to regulate anterior-posterior patterning in early embryonic development (Nunes et al., 2001 [PubMed 11287196]). See also PCGF2 (MIM 600346).[supplied by OMIM, Aug 2008]
  • Synonyms

    PCGF1; polycomb group ring finger 1; NSPC1; RNF68; RNF3A-2; 2010002K04Rik; polycomb group RING finger protein 1; RING finger protein 68; nervous system Polycomb-1;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PCGF1-1574H Recombinant Human PCGF1, His-tagged E.coli His 1-247aa
Human PCGF1-1308HCL Recombinant Human PCGF1 cell lysate N/A
Mouse PCGF1-12489M Recombinant Mouse PCGF1 Protein Mammalian Cell His
Mouse PCGF1-6548M-B Recombinant Mouse PCGF1 Protein Pre-coupled Magnetic Beads HEK293
Mouse PCGF1-6548M Recombinant Mouse PCGF1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat PCGF1-4297R Recombinant Rat PCGF1 Protein Mammalian Cell His
Rat PCGF1-3959R Recombinant Rat PCGF1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat PCGF1-3959R-B Recombinant Rat PCGF1 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish PCGF1-1648Z Recombinant Zebrafish PCGF1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

PCGF1 involved in several pathways and played different roles in them. We selected most pathways PCGF1 participated on our site, such as Signaling pathways regulating pluripotency of stem cells, which may be useful for your reference. Also, other proteins which involved in the same pathway with PCGF1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Signaling pathways regulating pluripotency of stem cellsIL6ST;GSK3B;IGF1;WNT5B;LHX5;WNT9B;ID4;WNT2B;PCGF3

PCGF1 has several biochemical functions, for example, protein C-terminus binding, protein binding, zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PCGF1 itself. We selected most functions PCGF1 had, and list some proteins which have the same functions with PCGF1. You can find most of the proteins on our site.

Function Related Protein
protein C-terminus bindingHAND2;VPS4B;DAB2;NCL;FBLN1;PPP2CA;AXIN1;DLG1;PPP1R9B
protein bindingCIZ1;AGFG1;CCDC151;SUMO2;RPGRIP1L;PBK;MED17;NLGN3;TAF3
zinc ion bindingTRIM55B;TADA2B;ANAPC11;RARA;PAM;MMP2;CSRP1A;APOBEC2A;TRIM68

PCGF1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PCGF1 here. Most of them are supplied by our site. Hope this information will be useful for your research of PCGF1.

RNF2; BCOR; RING1; CBX8; CBX6

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