pcgf1
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  • Official Full Name
  • polycomb group ring finger 1
  • Background
  • PCGF1 is a mammalian homolog of the Drosophila polycomb group genes, which act as transcriptional repressors to regulate anterior-posterior patterning in early embryonic development (Nunes et al., 2001 [PubMed 11287196]). See also PCGF2 (MIM 600346).[supplied by OMIM, Aug 2008]
  • Synonyms
  • PCGF1; polycomb group ring finger 1; NSPC1; RNF68; RNF3A-2; 2010002K04Rik; polycomb group RING finger protein 1; RING finger protein 68; nervous system Polycomb-1;
Cat.#:PCGF1-1574HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PCGF1, His-tagged
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Cat.#:PCGF1-12489MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse PCGF1 Protein
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Cat.#:PCGF1-4297RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat PCGF1 Protein
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Cat.#:PCGF1-1648ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish PCGF1
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Cat.#:PCGF1-1308HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human PCGF1 cell lysate
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Involved Pathway

PCGF1 involved in several pathways and played different roles in them. We selected most pathways PCGF1 participated on our site, such as Signaling pathways regulating pluripotency of stem cells, which may be useful for your reference. Also, other proteins which involved in the same pathway with PCGF1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Signaling pathways regulating pluripotency of stem cells
PCGF3; ID2; HESX1; PIK3CB; FZD9; BMI1; WNT2; WNT3A; FZD3; MAP2K2

Protein Function

PCGF1 has several biochemical functions, for example, protein C-terminus binding, protein binding, zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PCGF1 itself. We selected most functions PCGF1 had, and list some proteins which have the same functions with PCGF1. You can find most of the proteins on our site.
Function
Related Protein
Function protein C-terminus binding
Related Protein MKI67; KPNA3; SDCBP2; BCL10; KCNK3; PPP2CA; VPS4A; CSK; ITPR1; DST
Function protein binding
Related Protein FBXW8; LCORL; SNX31; Clec4n; TEX14; KSR1; IRAK2; PLEC; RHOV; DAO
Function zinc ion binding
Related Protein APIP; NPEPPS; LIMCH1A; ADH1; ZNF146; ADAMTS16; FBXO30; ZMYM4; RORAB; ADAMTS1

Interacting Protein

PCGF1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PCGF1 here. Most of them are supplied by our site. Hope this information will be useful for your research of PCGF1.
RNF2; BCOR; RING1; CBX8; CBX6