pex19
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  • Official Full Name
  • peroxisomal biogenesis factor 19
  • Background
  • This gene is necessary for early peroxisomal biogenesis. It acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. These disorders have at least 14 complementation groups, with more than one phenotype being observed for some complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of Zellweger syndrome (ZWS), as well as peroxisome biogenesis disorder complementation group 14 (PBD-CG14), which is also known as PBD-CGJ. Alternative splicing results in multiple transcript variants.
  • Synonyms
  • PEX19; peroxisomal biogenesis factor 19; peroxisomal farnesylated protein , PXF; D1S2223E; HK33; housekeeping gene; 33kD; PMP1; PMPI; PXMP1; peroxin-19; housekeeping gene, 33kD; 33 kDa housekeeping protein; peroxisomal farnesylated protein; PXF; FLJ55296
Cat.#:PEX19-1650HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PEX19, GST-tagged
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Cat.#:PEX19-27601THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PEX19, His-tagged
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Cat.#:PEX19-28143THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PEX19, His-tagged
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Cat.#:PEX19-2962HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PEX19, His-tagged
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Cat.#:PEX19-3637HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PEX19, His-tagged
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Cat.#:PEX19-12650MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse PEX19 Protein
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Cat.#:Pex19-1693MTag:His|T7
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Pex19 protein, His & T7-tagged
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Cat.#:PEX19-2318ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish PEX19
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Cat.#:PEX19-3289HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human PEX19 293 Cell Lysate
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Involved Pathway

PEX19 involved in several pathways and played different roles in them. We selected most pathways PEX19 participated on our site, such as Peroxisome, which may be useful for your reference. Also, other proteins which involved in the same pathway with PEX19 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Peroxisome
AGXTA; ACSL4A; CRAT; HAO2; NUDT19; PEX10; SLC25A17; AGXTB; MVK; FAR1

Protein Function

PEX19 has several biochemical functions, for example, ATPase binding, peroxisome membrane class-1 targeting sequence binding, protein N-terminus binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PEX19 itself. We selected most functions PEX19 had, and list some proteins which have the same functions with PEX19. You can find most of the proteins on our site.
Function
Related Protein
Function ATPase binding
Related Protein ATPIF1; ALDOB; DNAJB1; SLN; CHMP4A; SVIP; ATPIF1B; PLN; TAF9; ATPIF1A
Function peroxisome membrane class-1 targeting sequence binding
Related Protein PEX19
Function protein N-terminus binding
Related Protein GTF2H2; ERCC3; SMARCA4; NCOR2; ERCC5; ATM; MAP2K1; TBL1XR1; RPA3; BIRC2
Function protein binding
Related Protein HNRNPAB; TRAPPC5; NUDCD2; IP6K2; PRDM7; GTF2E1; CTDNEP1; OLIG3; MKNK1; TGFB1

Interacting Protein

PEX19 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PEX19 here. Most of them are supplied by our site. Hope this information will be useful for your research of PEX19.
PEX3