pfdn5
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  • Official Full Name
  • prefoldin subunit 5
  • Background
  • This gene encodes a member of the prefoldin alpha subunit family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils. The encoded protein may also repress the transcriptional activity of the proto-oncogene c-Myc. Alternatively spliced transcript variants encoding different isoforms have been described.
  • Synonyms
  • PFDN5; prefoldin subunit 5; prefoldin 5; MM 1; PFD5; 1190001O17Rik; 1700010A06Rik; c myc binding protein; c-myc binding protein MM 1; C-myc-binding protein Mm-1; D15Ertd697e; EIG 1; Eig1; MGC5329; MGC71907; MM1; Myc modulator 1; PFD5_HUMAN; myc modulator-1; c-myc binding protein; MM-1
Cat.#:PFDN5-28100THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PFDN5, His-tagged
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Cat.#:PFDN5-29723THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PFDN5, His-tagged
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Cat.#:PFDN5-359HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PFDN5, His-tagged
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Cat.#:PFDN5-3608HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PFDN5 protein, His-tagged
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Cat.#:PFDN5-12661MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse PFDN5 Protein
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Cat.#:PFDN5-3382RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey PFDN5 Protein, His-tagged
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Cat.#:PFDN5-6248ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish PFDN5
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Cat.#:PFDN5-3278HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human PFDN5 293 Cell Lysate
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Involved Pathway

PFDN5 involved in several pathways and played different roles in them. We selected most pathways PFDN5 participated on our site, such as Chaperonin-mediated protein folding, Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding, Metabolism of proteins, which may be useful for your reference. Also, other proteins which involved in the same pathway with PFDN5 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Chaperonin-mediated protein folding
FBXW2; PFDN2; PFDN5; FBXW4; CCT6A; PFDN4; FBXW5; TUBA3D; FBXW9; PFDN1
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding
CCT6A; CCT8; CCT5; CCT2; TUBB4A; TUBA3D; CCT3; PFDN4; CCT4; TUBA1B
Metabolism of proteins
DNAJC19; SLC34A2A; TGFBI; UBA2; DCP2; TRAPPC6A; SEC22C; DPH3; PFDN5; SLC25A12
Prefoldin mediated transfer of substrate to CCT/TriC
CCT6A; PFDN1; PFDN2; PFDN4; VBP1; CCT7; PFDN5; PFDN6
Protein folding
FBXW9; TBCB; FBXL5; ARL2; PFDN6; FBXW5; NOP56; TBCC; CCT7; FBXW2

Protein Function

PFDN5 has several biochemical functions, for example, protein binding, transcription corepressor activity, unfolded protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PFDN5 itself. We selected most functions PFDN5 had, and list some proteins which have the same functions with PFDN5. You can find most of the proteins on our site.
Function
Related Protein
Function protein binding
Related Protein ZC3H18; PELI2; CDKN3; PIK3CB; CAMK2D; PRIMPOL; COMMD9; EREG; DUSP21; SSBP3
Function transcription corepressor activity
Related Protein MAP3K10; SIAH2; LOXL2; SKOR1A; HOMEZ; YY1; HDAC5; SUFU; CIR1; IRF2BP2
Function unfolded protein binding
Related Protein CALRL2; MKKS; SYVN1; TMEM67; HSP26; CCT6A; PDRG1; CLPX; CRYAA; NPM1

Interacting Protein

PFDN5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PFDN5 here. Most of them are supplied by our site. Hope this information will be useful for your research of PFDN5.
vIRF-3; CALCOCO2; GLRX3; PSME3; IKZF3