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Official Full Name prefoldin subunit 6
Background PFDN6 is a subunit of the heteromeric prefoldin complex that chaperones nascent actin (see MIM 102560) and alpha- and;beta-tubulin (see MIM 602529 and MIM 191130, respectively) chains pending their transfer to the cytosolic chaperonin;containing TCP1 (MIM 186980) (CCT) complex (Hansen et al., 1999 (PubMed 10209023)).
Synonyms PFDN6; prefoldin subunit 6; HKE2, HLA class II region expressed gene KE2 , prefoldin 6; H2 KE2; KE 2; PFD6; H2KE2; HKE2; HLA class II region expressed gene KE2; KE2; KE2 protein; PFD6_HUMAN; Protein Ke2; prefoldin 6; KE-2; H2-KE2
    • Species :
    • Human
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human PFDN6-1656H Recombinant Human PFDN6, GST-tagged E.coli GST
    Human PFDN6-26966TH Recombinant Human PFDN6, His-tagged E.coli His
    Human PFDN6-3277HCL Recombinant Human PFDN6 293 Cell Lysate HEK293 N/A
    Human PFDN6-3407H Recombinant Human Prefoldin Subunit 6, His-tagged E.coli His
    Human PFDN6-4829H Recombinant Human PFDN6 Protein, GST-tagged Wheat Germ GST
    Rhesus Macaque PFDN6-3383R Recombinant Rhesus monkey PFDN6 Protein, His-tagged Mammalian Cell His
    Zebrafish PFDN6-10806Z Recombinant Zebrafish PFDN6 Mammalian Cell His

    PFDN6 involved in several pathways and played different roles in them. We selected most pathways PFDN6 participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with PFDN6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Chaperonin-mediated protein folding VBP1; CCT6A; TCP1; FKBP9; FBXW2; CCT8; PFDN6; TUBA1B; FBXL5; CCT2
    Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding CCT5; PFDN5; PFDN1; TUBB4B; CCT6A; PFDN4; TUBB4A; CCT8; CCT3; VBP1
    Metabolism of proteins CCDC59; CPB2; CMA1; SLC34A2A; ST6GALNAC1.2; NAPAB; SCMH1; FBXW4; SERP1; MTX2
    Prefoldin mediated transfer of substrate to CCT/TriC CCT6A; PFDN4; PFDN1; CCT7; PFDN5; PFDN6; PFDN2; VBP1
    Protein folding PFDN6; KIFC3; FBXW5; TBCC; FBXW4; NOP56; TBCD; FBXW2; PFDN4; FBXL5

    PFDN6 has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by PFDN6 itself. We selected most functions PFDN6 had, and list some proteins which have the same functions with PFDN6. You can find most of the proteins on our site.

    Function Related Protein
    chaperone binding BAG4; PACRG; HES1; HYOU1; CALR; TBCA; BAG2; PARK2; DNAJB5; RNF207
    unfolded protein binding LMAN1; CRYAA; SPG7; PFDN5; TCP1; TOMM20; CCT8; HSP26; DNAJA3B; GRXCR2

    PFDN6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PFDN6 here. Most of them are supplied by our site. Hope this information will be useful for your research of PFDN6.

    PRPF4; Tubb4b; MDM2; TUBA3E; MAP3K3; WRAP73; SPATA2; B4GALT2; Pfdn2; PPP6R2; POLR1A; PPP1CC; Ruvbl1; Vbp1; PPP2CB; MAPK7; HDAC1; Isy1; Wdr61; POLR3E

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