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Pfkfb1

  • Official Full Name

    6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • Mammalian cells
  • Sf9 Insect Cell
  • C
  • His
  • GST
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PFKFB1-214H Recombinant Human PFKFB1, GST-tagged Sf9 Insect Cell GST
Human PFKFB1-449H Recombinant Human PFKFB1 Mammalian Cell His
Human PFKFB1-767H Recombinant Human PFKFB1 Protein, His-tagged E.coli His
Human PFKFB1-3276HCL Recombinant Human PFKFB1 293 Cell Lysate HEK293 N/A
Human PFKFB1-4477H Recombinant Human PFKFB1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human PFKFB1-4869H Recombinant Human PFKFB1 Protein (Ser2-Tyr471), C-His tagged Mammalian cells C-His Ser2-Tyr471
Human PFKFB1-3832H Recombinant Human PFKFB1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human PFKFB1-3832H-B Recombinant Human PFKFB1 Protein Pre-coupled Magnetic Beads HEK293
Mouse Pfkfb1-4808M Recombinant Mouse Pfkfb1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat PFKFB1-4390R Recombinant Rat PFKFB1 Protein Mammalian Cell His
Rat PFKFB1-4050R Recombinant Rat PFKFB1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat PFKFB1-4050R-B Recombinant Rat PFKFB1 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish PFKFB1-10192Z Recombinant Zebrafish PFKFB1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Pfkfb1 Related Articles

Pfkfb1 involved in several pathways and played different roles in them. We selected most pathways Pfkfb1 participated on our site, such as Fructose and mannose metabolism, AMPK signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with Pfkfb1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Fructose and mannose metabolismGMPPB;Akr1b3;ALDOAB;ALDOC;FBP1;PFKMB;FBP2;FBP1A;GMDS
AMPK signaling pathwayPCK1;SIRT1;CREB5;INS;ELAVL1;EEF2K;G6PC2;IGF1R;PIK3R5

Pfkfb1 has several biochemical functions, for example, 6-phosphofructo-2-kinase activity, ATP binding, fructose-2,6-bisphosphate 2-phosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Pfkfb1 itself. We selected most functions Pfkfb1 had, and list some proteins which have the same functions with Pfkfb1. You can find most of the proteins on our site.

Function Related Protein
6-phosphofructo-2-kinase activityPFKFB4L;PFKFB3;PFKFB2A;PFKFB2;PFKFB4;PFKFB1
ATP bindingRENBP;VPS4B;ACVR1L;ACTR2B;MUSK;ACTR3;PDPK1A;KDRL;RECQL5
fructose-2,6-bisphosphate 2-phosphatase activityPFKFB1;C12orf5;PFKFB2;TIGARB;PFKFB3;PFKFB4;TIGARA
fructose-6-phosphate bindingPFKL;GCKR;PFKFB1
identical protein bindingCXADR;TRIP13;LRRK2;SMAD4;ROBO2;ATXN3;UGP2;TNK2;CLDND
kinase bindingCHP;CEBPA;PARK2;TNFAIP3;WWC3;PFKM;MOB4;SNAI1;BTG1
protein bindingOCIAD1;XRCC1;RHOH;CCDC28A;E2F5;TIRAP;HSPBAP1;TRIM67;TRAIP

Pfkfb1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Pfkfb1 here. Most of them are supplied by our site. Hope this information will be useful for your research of Pfkfb1.

GCK; PASK; MAPK3

Chesney, J; Clark, J; et al. Fructose-2,6-Bisphosphate synthesis by 6-Phosphofructo-2-Kinase/Fructose-2,6-Bisphosphatase 4 (PFKFB4) is required for the glycolytic response to hypoxia and tumor growth. ONCOTARGET 5:6670-6686(2014).
Yalcin, A; Clem, BF; et al. 6-Phosphofructo-2-kinase (PFKFB3) promotes cell cycle progression and suppresses apoptosis via Cdk1-mediated phosphorylation of p27. CELL DEATH & DISEASE 5:-(2014).
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