pfkfb1
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  • Official Full Name
  • 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
  • Synonyms
Cat.#:PFKFB1-214HTag:GST
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human PFKFB1, GST-tagged
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Cat.#:PFKFB1-449HTag:His
Source (Host):Mammalian CellsSpecies:Human
Product nameRecombinant Human PFKFB1
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Cat.#:PFKFB1-767HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PFKFB1 Protein, His-tagged
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Cat.#:PFKFB1-4390RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat PFKFB1 Protein
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Cat.#:PFKFB1-10192ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish PFKFB1
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Cat.#:PFKFB1-3276HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human PFKFB1 293 Cell Lysate
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Involved Pathway

Pfkfb1 involved in several pathways and played different roles in them. We selected most pathways Pfkfb1 participated on our site, such as Fructose and mannose metabolism, AMPK signaling pathway, Glucagon signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with Pfkfb1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Fructose and mannose metabolism
PFKFB4L; FBP2; ALDOAA; PFKFB3; FBP1A; TPI1A; DHRS13L1; ALDOB; TIGARA; ALDOCB
AMPK signaling pathway
ELAVL1; PRKAA1; Scd1; INS1; SLC2A4; AKT1S1; IRS1; CREB3L3; AKT2; PCK1
Glucagon signaling pathway
SIRT1; GCGR; CALML5; CREB3L3; PPP3R2; FOXO1; PPP3R1; ITPR1; CPT1C; CALM3

Protein Function

Pfkfb1 has several biochemical functions, for example, 6-phosphofructo-2-kinase activity, ATP binding, fructose-2,6-bisphosphate 2-phosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Pfkfb1 itself. We selected most functions Pfkfb1 had, and list some proteins which have the same functions with Pfkfb1. You can find most of the proteins on our site.
Function
Related Protein
Function 6-phosphofructo-2-kinase activity
Related Protein PFKFB2; PFKFB3; PFKFB2A; PFKFB4L; PFKFB4; PFKFB1
Function ATP binding
Related Protein KLHL8; RFC2; P2RX3A; EIF2AK4; SNRKB; CAMK1; SPHK1; HYOU1; CAMK2B; DDX11
Function fructose-2,6-bisphosphate 2-phosphatase activity
Related Protein C12orf5; PFKFB4; PFKFB3; PFKFB1; PFKFB2; TIGARA; TIGARB
Function fructose-6-phosphate binding
Related Protein PFKL; GCKR; PFKFB1
Function identical protein binding
Related Protein DESI1; TPCN2; SNX16; SID4; REG3B; ERBB2; CRYAB; COL18A1; POU3F2; VIL1
Function kinase binding
Related Protein TOLLIP; CAB39; MIDN; PFKFB1; LDHA; NTRK1; TAX1BP1; SP100; LDHB; JAKMIP3
Function protein binding
Related Protein GRIN1; NRL; ELF1; RALYL; LENG1; RCHY1; FBXW2; TNNC2; TTC19; Acr

Interacting Protein

Pfkfb1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Pfkfb1 here. Most of them are supplied by our site. Hope this information will be useful for your research of Pfkfb1.
GCK; PASK; MAPK3

Pfkfb1 Related Articles

Chesney, J; Clark, J; et al. Fructose-2,6-Bisphosphate synthesis by 6-Phosphofructo-2-Kinase/Fructose-2,6-Bisphosphatase 4 (PFKFB4) is required for the glycolytic response to hypoxia and tumor growth. ONCOTARGET 5:6670-6686(2014).
Yalcin, A; Clem, BF; et al. 6-Phosphofructo-2-kinase (PFKFB3) promotes cell cycle progression and suppresses apoptosis via Cdk1-mediated phosphorylation of p27. CELL DEATH & DISEASE 5:-(2014).