Recombinant Human PFKFB1 Protein, Myc/DDK-tagged, C13 and N15-labeled
Cat.No. : | PFKFB1-4477H |
Product Overview : | PFKFB1 MS Standard C13 and N15-labeled recombinant protein (NP_002616) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the family of bifunctional 6-phosphofructo-2-kinase:fructose-2,6-biphosphatase enzymes. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis. Multiple alternatively spliced transcript variants have been found for this gene. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 54.7 kDa |
AA Sequence : | MSPEMGELTQTRLQKIWIPHSSGSS RLQRRRGSSIPQFTNSPTMVIMVGL PARGKTYISTKLTRYLNWIGTPTKV FNLGQYRREAVSYKNYEFFLPDNME ALQIRKQCALAALKDVHNYLSHEEG HVAVFDATNTTRERRSLILQFAKEH GYKVFFIESICNDPGIIAENIRQVK LGSPDYIDCDREKVLEDFLKRIECY EVNYQPLDEELDSHLSYIKIFDVGT RYMVNRVQDHIQSRTVYYLMNIHVT PRSIYLCRHGESELNIRGRIGGDSG LSVRGKQYAYALANFIQSQGISSLK VWTSHMKRTIQTAEALGVPHEQWKA LNEIDAGVCEEMTYEEIQEHYPEEF ALRDQDKYRYRYPKGESYEDLVQRL EPVIMELERQENVLVICHQAVMRCL LAYFLDKSSDELPYLKCPLHTVLKL TPVAYGCKVESIYLNVEAVNTHREK PENVDITREPEEALDTVPAHYTRTR PLEQKLISEEDLAANDILDYKDDDD KV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 [Homo sapiens (human) ] |
Official Symbol : | PFKFB1 |
Synonyms : | PFKFB1; F6PK; HL2K; PFRX; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1; 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1; PFK/FBPase 1; 6PF-2-K/Fru-2,6-P2ase 1; 6PF-2-K/Fru-2,6-P2ASE liver isozyme; fructose-6-phosphate,2-kinase:fructose-2,6-bisphosphatase; EC 2.7.1.105; EC 3.1.3.46 |
Gene ID : | 5207 |
mRNA Refseq : | NM_002625 |
Protein Refseq : | NP_002616 |
MIM : | 311790 |
UniProt ID : | P16118 |
Products Types
◆ Recombinant Protein | ||
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Pfkfb1-4808M | Recombinant Mouse Pfkfb1 Protein, Myc/DDK-tagged | +Inquiry |
PFKFB1-3832H | Recombinant Human PFKFB1 Protein, His (Fc)-Avi-tagged | +Inquiry |
PFKFB1-767H | Recombinant Human PFKFB1 Protein, His-tagged | +Inquiry |
PFKFB1-449H | Recombinant Human PFKFB1 | +Inquiry |
◆ Lysates | ||
PFKFB1-3276HCL | Recombinant Human PFKFB1 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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