pi4kb
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  • Official Full Name
  • phosphatidylinositol 4-kinase, catalytic, beta
  • Background
  • Phosphorylates phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol-1,4,5,-trisphosphate (PIP). May regulate Golgi disintegration/reorganization during mitosis, possibly via its phosphorylation. Involved in Golgi-to-plasma membrane trafficking.
  • Synonyms
  • PI4KB; phosphatidylinositol 4-kinase, catalytic, beta; PIK4CB; phosphatidylinositol 4-kinase beta; PI4K BETA; pi4K92; PtdIns 4-kinase beta; type III phosphatidylinositol 4-kinase beta; phosphatidylinositol 4-kinase, wortmannin-sensitive; NPIK; PI4
Cat.#:PI4KB-1077Tag:GST
Source (Host):Insect cellsSpecies:Human
Product nameRecombinant Human PI4KB protein, GST-tagged
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Cat.#:PI4KB-1077HTag:GST
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human PI4KB, GST-tagged
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Cat.#:PI4KB-162HTag:GST
Source (Host):Insect cellsSpecies:Human
Product nameRecombinant Human PI4KB protein, GST-tagged, Active
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Cat.#:PI4KB-1702HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PI4KB, GST-tagged
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Cat.#:PI4KB-30364THTag:N/A
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human PI4KB
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Cat.#:PI4KB-12766MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse PI4KB Protein
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Cat.#:PI4KB-4440RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat PI4KB Protein
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Cat.#:PI4KB-3452ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish PI4KB
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Cat.#:PI4KB-3206HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human PI4KB 293 Cell Lysate
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Involved Pathway

PI4KB involved in several pathways and played different roles in them. We selected most pathways PI4KB participated on our site, such as Inositol phosphate metabolism, Metabolic pathways, Phosphatidylinositol signaling system, which may be useful for your reference. Also, other proteins which involved in the same pathway with PI4KB were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Inositol phosphate metabolism
PIP5K2; PLCD4; PIK3CA; PIK3C3; OCRL; IP6K3; NUDT3B; SYNJ2; NUDT4A; INPP5A
Metabolic pathways
PTGES3B; GLUD1; PLA2G5; HMBSB; SMPD2A; NDUFAB1; ST6GAL1; GNSA; CYP11B1; MTHFD1L
Phosphatidylinositol signaling system
INPP4B; PIP4K2B; PIK3R5; IMPA1; CALM2B; PI4KA; ITPKA; PPIP5K1; INPP5D; PIP4K2C

Protein Function

PI4KB has several biochemical functions, for example, 1-phosphatidylinositol 4-kinase activity, ATP binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PI4KB itself. We selected most functions PI4KB had, and list some proteins which have the same functions with PI4KB. You can find most of the proteins on our site.
Function
Related Protein
Function 1-phosphatidylinositol 4-kinase activity
Related Protein PI4KB; PI4KA; PI4K2B; PI4K2A; PI4KAA; PI4KAB
Function ATP binding
Related Protein DDR1; SUCLA2; MYO1F; ATAD1B; CLK2B; VPS4B; RBM4.3; PRKACG; PIK3R4; HUNK
Function protein binding
Related Protein LBP; CCND3; NINJ2; MSMB; NUMBL; RBBP7; WWP1; HIST1H4B; MYZAP; CDC25C

Interacting Protein

PI4KB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PI4KB here. Most of them are supplied by our site. Hope this information will be useful for your research of PI4KB.
YWHAQ; YWHAB; YWHAG; ACBD3; NS; xmd8-92; biotin_acyl-p_probe; SFN; UTRN; KBTBD7

PI4KB Related Articles

Stevenson, JM; Perera, IY; et al. A phosphatidylinositol 4-kinase pleckstrin homology domain that binds phosphatidylinositol 4-monophosphate. JOURNAL OF BIOLOGICAL CHEMISTRY 273:22761-22767(1998).
WONG, K; CANTLEY, LC; et al. CLONING AND CHARACTERIZATION OF A HUMAN PHOSPHATIDYLINOSITOL 4-KINASE. JOURNAL OF BIOLOGICAL CHEMISTRY 269:28878-28884(1994).