pigr
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  • Official Full Name
  • polymeric immunoglobulin receptor
  • Background
  • This gene is a member of the immunoglobulin superfamily. The encoded poly-Ig receptor binds polymeric immunoglobulin molecules at the basolateral surface of epithelial cells; the complex is then transported across the cell to be secreted at the apical surface. A significant association was found between immunoglobulin A nephropathy and several SNPs in this gene.
  • Synonyms
  • PIGR; polymeric immunoglobulin receptor; poly-Ig receptor; hepatocellular carcinoma associated protein TB6; hepatocellular carcinoma-associated protein TB6; FLJ22667; MGC125361; MGC125362
Cat.#:PIGR-1483BTag:His
Source (Host):YeastSpecies:Bovine
Product nameRecombinant Bovine PIGR Protein (400-599 aa), His-tagged
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Cat.#:PIGR-719BTag:His
Source (Host):E. coliSpecies:Bovine
Product nameRecombinant Bovine PIGR Protein (400-599 aa), His-tagged
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Cat.#:PIGR-1470HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PIGR protein, His-tagged
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Cat.#:PIGR-338HTag:His
Source (Host):Mammalian CellsSpecies:Human
Product nameRecombinant Human PIGR
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Cat.#:PIGR-495HTag:His
Source (Host):NSO cellsSpecies:Human
Product nameRecombinant Human PIGR, His-tagged
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Cat.#:PIGR-829HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human PIGR, His tagged
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Cat.#:PIGR-830HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human PIGR Protein, His-tagged
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Cat.#:Pigr-1018MTag:His
Source (Host):NSO CellsSpecies:Mouse
Product nameRecombinant Mouse Pigr Protein, His-tagged
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Cat.#:Pigr-1471MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Pigr protein, His-tagged
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Cat.#:Pigr-1472MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Pigr protein, His-tagged
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Cat.#:Pigr-830MTag:His
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Pigr, His tagged
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Cat.#:Pigr-1473RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Pigr protein, His-tagged
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Cat.#:Pigr-1474RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Pigr protein, His-tagged
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Cat.#:Pigr-1475RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Pigr protein, His-tagged
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Cat.#:PIGR-3436CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken PIGR
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Cat.#:PIGR-8496ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish PIGR
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Cat.#:PIGR-1468CTag:His
Source (Host):E. coliSpecies:Cattle
Product nameRecombinant Cattle PIGR protein, His-tagged
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Cat.#:PIGR-1469CTag:His
Source (Host):E. coliSpecies:Cattle
Product nameRecombinant Cattle PIGR protein, His-tagged
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Cat.#:PIGR-2868HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human PIGR cell lysate
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Cat.#:PIGR-2867MCLTag:
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse PIGR cell lysate
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Involved Pathway

PIGR involved in several pathways and played different roles in them. We selected most pathways PIGR participated on our site, such as Intestinal i, ne network for IgA production, which may be useful for your reference. Also, other proteins which involved in the same pathway with PIGR were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Intestinal i
H2-AB1; IL6; HLA-DPA1; CXCR4; IL5; AICDA; ICOS; HLA-DRB4; TNFRSF13B; HLA-DQA1
ne network for IgA production
HLA-DPB1; MAP3K14; ITGB7; Il2; CXCR4A; TGFB1A; CD28; HLA-DQB1; TNFSF13; CXCL12B

Protein Function

PIGR has several biochemical functions, for example, polymeric immunoglobulin receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PIGR itself. We selected most functions PIGR had, and list some proteins which have the same functions with PIGR. You can find most of the proteins on our site.
Function
Related Protein
Function polymeric immunoglobulin receptor activity
Related Protein PIGR

Interacting Protein

PIGR has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PIGR here. Most of them are supplied by our site. Hope this information will be useful for your research of PIGR.
SGK1; Dynll1; MIS12; cona_canen; CDK6; STK4

PIGR Related Articles

Kaetzel, CS; et al. Cooperativity among secretory IgA, the polymeric immunoglobulin receptor, and the gut microbiota promotes host-microbial mutualism. IMMUNOLOGY LETTERS 162:10-21(2014).
Armitage, CW; O'Meara, CP; et al. Evaluation of intra- and extra-epithelial secretory IgA in chlamydial infections. IMMUNOLOGY 143:520-530(2014).