pmpcb
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  • Official Full Name
  • peptidase (mitochondrial processing) beta
  • Background
  • This gene is a member of the peptidase M16 family and encodes a protein with a zinc-binding motif. This protein is located in the mitochondrial matrix and catalyzes the cleavage of the leader peptides of precursor proteins newly imported into the mitochondria, though it only functions as part of a heterodimeric complex.
  • Synonyms
  • PMPCB; peptidase (mitochondrial processing) beta; mitochondrial-processing peptidase subunit beta; MPPB; MPPP52; Beta MPP; BetaMPP; Mitochondrial processing peptidase subunit beta; MPP11; P 52; P52; Peptidase mitichondrial processing beta; mitochondrial processing peptidase beta subunit; P-52; Beta-MPP
Cat.#:PMPCB-2146HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human PMPCB Protein, MYC/DDK-tagged
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Cat.#:PMPCB-1811HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PMPCB, GST-tagged
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Cat.#:PMPCB-281HTag:GST
Source (Host):Species:Human
Product nameRecombinant Human PMPCB, GST-tagged
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Cat.#:PMPCB-282HTag:GST
Source (Host):Species:Human
Product nameRecombinant Human PMPCB, GST-tagged
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Cat.#:PMPCB-13019MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse PMPCB Protein
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Cat.#:PMPCB-4543RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat PMPCB Protein
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Cat.#:PMPCB-796CTag:His
Source (Host):Mammalian CellsSpecies:Cynomolgus Monkey
Product nameRecombinant Cynomolgus PMPCB Protein, His-tagged
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Cat.#:PMPCB-4328CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken PMPCB
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Cat.#:PMPCB-2055ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish PMPCB
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Cat.#:PMPCB-284HTag:DDK
Source (Host):HEK293TSpecies:Human
Product nameNative Human PMPCB, DDK-tagged
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Involved Pathway

PMPCB involved in several pathways and played different roles in them. We selected most pathways PMPCB participated on our site, such as Metabolism of proteins, Mitochondrial protein import, which may be useful for your reference. Also, other proteins which involved in the same pathway with PMPCB were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Metabolism of proteins
KLK13; IGFBP6A; TIMM9; ST6GAL2B; CPB2; NSMCE1; FBXW5; TBCC; ADAMTS13; SEC22A
Mitochondrial protein import
TOMM70A; SAMM50; LDHD; SLC25A13; DNAJC19; TOMM6; SLC25A12; TIMM44; TIMM50; TOMM22

Protein Function

PMPCB has several biochemical functions, for example, metalloendopeptidase activity, zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PMPCB itself. We selected most functions PMPCB had, and list some proteins which have the same functions with PMPCB. You can find most of the proteins on our site.
Function
Related Protein
Function metalloendopeptidase activity
Related Protein MEP1A.1; ADAM12; MMP14A; PMPCB; ADAM20; MMP7; MMP20; BMP1; HE1A; MIPEP
Function zinc ion binding
Related Protein MSL2A; TRIM35-20; HE1A; RNF222; CPDB; SERPINB1A; NSMCE1; ZMIZ1; RNF187; SQSTM1

Interacting Protein

PMPCB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PMPCB here. Most of them are supplied by our site. Hope this information will be useful for your research of PMPCB.
MARK3; ICT1; CLPP; SIRT4

PMPCB Related Articles

McCord, LA; Liang, WGG; et al. Conformational states and recognition of amyloidogenic peptides of human insulin-degrading enzyme. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 110:13827-13832(2013).
Wattiaux, R; Coninck, SWD; et al. Lysosornes and Fas-mediated liver cell death. BIOCHEMICAL JOURNAL 403:89-95(2007).