PNLIP
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Official Full Name
pancreatic lipase
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Overview
Pancreatic lipase, also known as pancreatic triacylglycerol lipase, is secreted from the pancreas, and is the primary lipase (enzyme) that hydrolyzes (breaks down) dietary fat molecules in the human digestive system, converting triglyceride substrates found in ingested oils to monoglycerides and free fatty acids. Triacylglycerol + H2O diacylglycerol + a fatty acid anion Bile salts secreted from the liver and stored in gallbladder are released into the duodenum where they coat and emulsify large fat droplets into smaller droplets, thus increasing the overall surface area of the fat, which allows the lipase to break apart the fat more effectively. The resulting monomers (2 free fatty acids and one 2-monoacylglycerol) are then moved by way of peristalsis along the small intestine to be absorbed into the lymphatic system by a specialized vessel called a lacteal. This protein belongs to pancreatic lipase family. -
Synonyms
PNLIP; pancreatic lipase; PL; PTL; pancreatic triacylglycerol lipase; OTTHUMP00000020564; triacylglycerol acylhydrolase; Lipase;
- Recombinant Proteins
- Cell & Tissue Lysates
- Transfected Stable Cell Lines
- Native Proteins
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- Pig
- Rat
- E.coli
- HEK293
- HEK293T
- Human Cell
- Human Pancreas
- In Vitro Cell Free System
- Mammalian Cell
- Porcine Pancreas
- Wheat Germ
- His
- His (Fc)
- Avi
- His|SUMO
- His|T7
- Myc
- DDK
- Myc|DDK
- N/A
- N
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
---|---|---|---|---|---|---|
Human | PNLIP-30776TH | Recombinant Human PNLIP | Wheat Germ | N/A | 465 amino acids | |
Human | PNLIP-8599H | Recombinant Human PNLIP, His-tagged | HEK293 | His | Met1-Cys465 | |
Human | PNLIP-1246HCL | Recombinant Human PNLIP cell lysate | Human Cell | N/A | ||
Human | PNLIP-13H | Recombinant human pancreatic lipase Reference Standard | N/A | |||
Human | PNLIP-2603H | Recombinant Human PNLIP Protein, His-tagged | E.coli | N-His | Pro245-Cys465 | |
Human | PNLIP-12H | Human pancreatic lipase from pancreatic juice Reference Standard | N/A | |||
Human | PNLIP-8203H | Native Human Pancreatic Lipase | Human Pancreas | N/A | ||
Human | PNLIP-28H | Recombinant Human PNLIP Protein, N-His Tagged | E.coli | N-His | ||
Human | PNLIP-2415H | Recombinant Human PNLIP Protein, MYC/DDK-tagged | HEK293 | Myc/DDK | ||
Human | PNLIP-8205H | Native Human Pancreas Lipase | Human Pancreas | N/A | ||
Human | PNLIP-375HF | Recombinant Full Length Human PNLIP Protein | In Vitro Cell Free System | 465 amino acids | ||
Mouse | Pnlip-1331M | Recombinant Mouse Pnlip Protein, His-SUMO-tagged | E.coli | His/SUMO | ||
Mouse | Pnlip-6977M | Recombinant Mouse Pnlip protein, His & T7-tagged | E.coli | His/T7 | Gly201~Leu412 (Accession # Q6P8U6) | |
Mouse | Pnlip-4964M | Recombinant Mouse Pnlip Protein, Myc/DDK-tagged | HEK293T | Myc/DDK | ||
Rat | PNLIP-4545R | Recombinant Rat PNLIP Protein | Mammalian Cell | His | ||
Rat | Pnlip-26R | Recombinant Rat Pnlip protein, His-tagged | E.coli | His | Ser47~His280 | |
Rat | PNLIP-4205R-B | Recombinant Rat PNLIP Protein Pre-coupled Magnetic Beads | HEK293 | |||
Rat | PNLIP-4205R | Recombinant Rat PNLIP Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Pig | PNLIP-1175P | Native Porcine Pancreatic Lipase | Porcine Pancreas | N/A | ||
Chicken | PNLIP-4795C | Recombinant Chicken PNLIP | Mammalian Cell | His |
- Involved Pathway
- Protein Function
- Interacting Protein
- PNLIP Related Articles
PNLIP involved in several pathways and played different roles in them. We selected most pathways PNLIP participated on our site, such as Glycerolipid metabolism, Metabolic pathways, Pancreatic secretion, which may be useful for your reference. Also, other proteins which involved in the same pathway with PNLIP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Glycerolipid metabolism | PNLIP;GLYCTK;Akr1b3;DAK;TAE1;AKR1A1;DGAT1A;ALDH3A2A;DGKB |
Metabolic pathways | PDHA1B;ENPP7;IMPDH2;GOT2;SPTLC3;GPT2;PLA2G4AA;CEPT1B;DNMT3A |
Pancreatic secretion | CELA2B;SLC26A3;CPB1;ATP2B1;Slc4a2;PRSS2;ATP1A2;CLCA4;TPCN2 |
Fat digestion and absorption | PLA2G10;DGAT2;PLA2G2D;DGAT1;PLA2G2A;GOT2;PLA2G1B;PNLIPRP1;ABCA1 |
Vitamin digestion and absorption | TCN2;APOB;SLC52A3;MMACHC;FOLH1;APOA4;PNLIP;CUBN;RBP2 |
PNLIP has several biochemical functions, for example, metal ion binding, triglyceride lipase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PNLIP itself. We selected most functions PNLIP had, and list some proteins which have the same functions with PNLIP. You can find most of the proteins on our site.
Function | Related Protein |
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metal ion binding | ZNF70;RXRGA;YOD1;MORC2B;ZNFX1;ATP2B1;ZNF10;EXOG;ZFP260 |
triglyceride lipase activity | PNPLA3;PNPLA4;CES5A;AADAC;LIPC;CES1;PNLIPRP3;PNPLA2;LPL |
PNLIP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PNLIP here. Most of them are supplied by our site. Hope this information will be useful for your research of PNLIP.
CLPS; YWHAE
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