|Official Full Name||patatin-like phospholipase domain containing 8|
|Background||This gene encodes a member of the patatin-like phospholipase domain containing protein family. Members of this family;are phospholipases which catalyze the cleavage of fatty acids from membrane phospholipids. The product of this gene is;a calcium-independent phospholipase. A pseudogene of this gene is located on the X chromosome. Multiple transcript;variants encoding different isoforms have been found for this gene.|
|Synonyms||PNPLA8; patatin-like phospholipase domain containing 8; calcium-independent phospholipase A2-gamma; IPLA2(GAMMA); IPLA2 2; IPLA2G; PNPLA-gamma; iPLA2 gamma; iPLA2-gamma; patatin-like phospholipase domain-containing protein 8; membrane-associated calcium-i|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
PNPLA8 involved in several pathways and played different roles in them. We selected most pathways PNPLA8 participated on our site, such as Acyl chain remodelling of PC, Acyl chain remodelling of PE, Eicosanoid Synthesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with PNPLA8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Acyl chain remodelling of PC||PLB1; PLA2G16; PNPLA8; PLA2G4B; PLBD1|
|Acyl chain remodelling of PE||PLA2G4B; PLBD1; PNPLA8; PLA2G16|
|Eicosanoid Synthesis||PNPLA8; DPEP1; ALOX5AP|
|Glycerophospholipid biosynthesis||CEPT1A; PLBD1; CHKA; BCHE; AGPAT6; CPNE6; PLA2G16; PEMT; PHOSPHO1; MGLL|
|Metabolism||TIAM2; GLIPR1; LRPPRC; LYPLA1; NFYBB; ARSF; NUDT3; ARSI; NUDT4; SLC25A21|
|Metabolism of lipids and lipoproteins||VAPB; GLTPD1; GGTLC1; COL4A3BP; FABP12; MED22; ARSD; PIK3R6; FABP11B; AKR1C2|
|Phospholipid metabolism||ABHD3; CPNE1; ABHD4; CDS1; ARF3; CEPT1; CPNE7; PLBD1; PNPLA8; PHOSPHO1|
PNPLA8 has several biochemical functions, for example, calcium-independent phospholipase A2 activity, hydrolase activity, lysophospholipase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PNPLA8 itself. We selected most functions PNPLA8 had, and list some proteins which have the same functions with PNPLA8. You can find most of the proteins on our site.
|calcium-independent phospholipase A2 activity||PLA2G4C; PLA2G15; PLA2G7; PNPLA8|
|hydrolase activity||CTSL.1; SNRNP200; ATAD1A; AGBL1; AGBL4; GALCA; ASAH1A; ABHD2B; PTPN4B; PTPN23A|
|lysophospholipase activity||LYPLA1; PNPLA7; Cel; PLA2G4AA; PNPLA8; PLA2G4A; LGALS13; PNPLA6; PNPLA7A; MGLL|
PNPLA8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PNPLA8 here. Most of them are supplied by our site. Hope this information will be useful for your research of PNPLA8.