PNPO Protein, pyridoxamine 5-phosphate oxidase

PNPO

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PNPO

Official Full Name pyridoxamine 5-phosphate oxidase
Background The enzyme encoded by this gene catalyzes the terminal, rate-limiting step in the synthesis of pyridoxal 5-phosphate, also known as vitamin B6. Vitamin B6 is a required co-factor for enzymes involved in both homocysteine metabolism and synthesis of neurotransmitters such as catecholamine. Mutations in this gene result in pyridoxamine 5-phosphate oxidase (PNPO) deficiency, a form of neonatal epileptic encephalopathy.
Synonyms PNPO; pyridoxamine 5-phosphate oxidase; pyridoxine 5 phosphate oxidase; pyridoxine-5-phosphate oxidase; PDXPO; EC 1.4.3.5; FLJ10535; PNPO_HUMAN; Pyridoxal 5 phosphate synthase; pyridoxamine 5 phosphate oxidase; Pyridoxamine phosphate oxidase; Pyridoxamine-phosphate oxidase; pyridoxal 5-phosphate synthase; pyridoxine 5-phosphate oxidase
    • Species :
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Mouse
    • Tag :
    • GST
    • His
    • T7
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CAB-11473MH Mouse Anti-Human PNPO Monoclonal Antibody Mouse N/A
    Human PNPO-1820H Recombinant Human PNPO, GST-tagged E.coli GST
    Human PNPO-27512TH Recombinant Human PNPO, His-tagged E.coli His
    Human PNPO-2868H Recombinant Human Pyridoxamine 5 -phosphate Oxidase, His-tagged E.coli His
    Human PNPO-3065HCL Recombinant Human PNPO 293 Cell Lysate HEK293 N/A
    Mouse PNPO-13048M Recombinant Mouse PNPO Protein Mammalian Cell His
    Mouse Pnpo-8034M Recombinant Mouse Pnpo protein, His & T7-tagged E.coli His/T7
    Rat PNPO-4553R Recombinant Rat PNPO Protein Mammalian Cell His
    Rhesus Macaque PNPO-3497R Recombinant Rhesus monkey PNPO Protein, His-tagged Mammalian Cell His
    Zebrafish PNPO-8118Z Recombinant Zebrafish PNPO Mammalian Cell His

    PNPO involved in several pathways and played different roles in them. We selected most pathways PNPO participated on our site, such as Vitamin B metabolism, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with PNPO were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Vitamin B metabolism PDXKB; PNPO; AOX2P; PSAT1; AOX3; AOX4; AOX3L1; AOX1; PDXK; PDXKA
    Metabolic pathways RRM2; MTMR7B; GBE1; ACMSD; CPS1; BCAT2; EXTL1; ALG13; PSPH; FUT9A

    PNPO has several biochemical functions, for example, FMN binding, pyridoxamine-phosphate oxidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PNPO itself. We selected most functions PNPO had, and list some proteins which have the same functions with PNPO. You can find most of the proteins on our site.

    Function Related Protein
    FMN binding TYW1B; NOS2A; TYW1; HAO2; NOS3; DHODH; NOS2B; NOS2; NOS1; POR
    pyridoxamine-phosphate oxidase activity PNPO

    PNPO has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PNPO here. Most of them are supplied by our site. Hope this information will be useful for your research of PNPO.

    MYO1C; Junb

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