PON2

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PON2

Official Full Name paraoxonase 2
Background This gene encodes a member of the paraoxonase gene family, which includes three known members located adjacent to each other on the long arm of chromosome 7. The encoded protein is ubiquitously expressed in human tissues, membrane-bound, and may act as a cellular antioxidant, protecting cells from oxidative stress. Hydrolytic activity against acylhomoserine lactones, important bacterial quorum-sensing mediators, suggests the encoded protein may also play a role in defense responses to pathogenic bacteria. Mutations in this gene may be associated with vascular disease and a number of quantitative phenotypes related to diabetes. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Synonyms PON2; paraoxonase 2; serum paraoxonase/arylesterase 2; PON 2; A-esterase 2; arylesterase 2; paraoxonase nirs; aromatic esterase 2; serum aryldialkylphosphatase 2;
    • Species :
    • Chicken
    • Cynomolgus Monkey
    • Human
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Tag :
    • His
    • T7
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human PON2-3013HCL Recombinant Human PON2 293 Cell Lysate HEK293 N/A
    Human PON2-30704TH Recombinant Human PON2, His-tagged E.coli His
    Human PON2-50H Recombinant Human Paraoxonase 2, His-tagged E.coli His
    Mouse Pon2-7914M Recombinant Mouse Pon2 protein, His & T7-tagged E.coli His/T7
    Rat PON2-4578R Recombinant Rat PON2 Protein Mammalian Cell His
    Cynomolgus Monkey PON2-802C Recombinant Cynomolgus PON2 Protein, His-tagged Mammalian Cell His
    Chicken PON2-4494C Recombinant Chicken PON2 Mammalian Cell His
    Zebrafish PON2-12006Z Recombinant Zebrafish PON2 Mammalian Cell His

    PON2 involved in several pathways and played different roles in them. We selected most pathways PON2 participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with PON2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Metabolic pathways PDHA1A; DGKZ; HK1; AKR1C3; HAO1; NDUFS8A; NMRK1; PDHA2; NDUFC2-KCTD14; CYP7A1

    PON2 has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by PON2 itself. We selected most functions PON2 had, and list some proteins which have the same functions with PON2. You can find most of the proteins on our site.

    Function Related Protein
    arylesterase activity PON2; Car2; APMAP; PON1; C20orf3; PON3; CA1; CAR1; CA2
    identical protein binding GSTM3; IAPP; PTS; SCAND1; RAD51; GOT2B; TTC32; AXIN1; LRRK2; EPOR
    metal ion binding IMPDH1A; ZC3H18; GFI1AA; ZDHHC21; ATP1A1A.1; ZSCAN2; FEZF2; ZNF710; PDE7A; HBBE2

    PON2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PON2 here. Most of them are supplied by our site. Hope this information will be useful for your research of PON2.

    env; env; GRB2; ERBB3

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