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Official Full Name phosphoribosyl pyrophosphate amidotransferase
Background The protein encoded by this gene is a member of the purine/pyrimidine phosphoribosyltransferase family. It is a regulatory allosteric enzyme that catalyzes the first step of de novo purine nucleotide biosythetic pathway. This gene and PAICS/AIRC gene, a bifunctional enzyme catalyzing steps six and seven of this pathway, are located in close proximity on chromosome 4, and divergently transcribed from an intergenic region.
Synonyms PPAT; phosphoribosyl pyrophosphate amidotransferase; amidophosphoribosyltransferase; GPAT; PRAT; Amidophosphoribosyltransferase [Precursor]; ATASE; Glutamine phosphoribosylpyrophosphate amidotransferase; Glutamine PRPP amidotransferase; glutamine phosphoribosylpyrophosphatate amidotransferase
    • Species :
    • Chicken
    • E.coli
    • Human
    • Rat
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • E.Coli or Yeast
    • HEK293
    • Mammalian Cell
    • Tag :
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human PPAT-1874H Recombinant Human PPAT, His-tagged E.coli His
    Human PPAT-2983HCL Recombinant Human PPAT 293 Cell Lysate HEK293 N/A
    Rat Ppat-3408R Recombinant Rat Ppat, His-tagged E.Coli or Yeast His
    Rat PPAT-4596R Recombinant Rat PPAT Protein Mammalian Cell His
    Rhesus Macaque PPAT-3538R Recombinant Rhesus monkey PPAT Protein, His-tagged Mammalian Cell His
    Chicken PPAT-1219C Recombinant Chicken PPAT Mammalian Cell His
    Zebrafish PPAT-5263Z Recombinant Zebrafish PPAT Mammalian Cell His
    E.coli ppa-3594E Recombinant E.coli ppa, His-tagged E.coli His

    PPAT involved in several pathways and played different roles in them. We selected most pathways PPAT participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with PPAT were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Purine metabolism PDE6A; POLR2GL; NME5; ADKB; IMPDH1B; NT5C3A; ZNRD1; POLE4; NPR1A; GDA
    Alanine, aspartate and glutamate metabolism GPT; ABAT; ADSSL1; GLULB; ADSL; ALDH4A1; AGXT; GAD1B; ASS1; NIT2
    Metabolic pathways GMPPAB; PCYT1AB; MCEE; GPIB; ACSL1; UGT1A9; PIP5K1AB; ENO2; NT5C3L; NDUFS6

    PPAT has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by PPAT itself. We selected most functions PPAT had, and list some proteins which have the same functions with PPAT. You can find most of the proteins on our site.

    Function Related Protein
    4 iron, 4 sulfur cluster binding NTHL1; CDKAL1; NDUFS8; ACO1; ACO2; DPYD; DNA2; RSAD1; ISCUB; DPYDB
    amidophosphoribosyltransferase activity PPAT
    metal ion binding ERI3; EBF3A; PPP2CA; HDDC3; DGKQ; NR1D1; ZNF800B; ZDHHC21; HBB-B2; ALKBH7

    PPAT has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PPAT here. Most of them are supplied by our site. Hope this information will be useful for your research of PPAT.

    ATXN1; EPT1

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