prodh
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  • Official Full Name
  • proline dehydrogenase (oxidase) 1
  • Background
  • This gene encodes a mitochondrial protein that catalyzes the first step in proline degradation. Mutations in this gene are associated with hyperprolinemia type 1 and susceptibility to schizophrenia 4 (SCZD4). This gene is located on chromosome 22q11.21, a region which has also been associated with the contiguous gene deletion syndromes, DiGeorge and CATCH22. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
  • Synonyms
  • PRODH; proline dehydrogenase (oxidase) 1; proline dehydrogenase (proline oxidase ); proline dehydrogenase 1, mitochondrial; HSPOX2; PIG6; PRODH1; PRODH2; TP53I6; proline oxidase 2; p53-induced gene 6 protein; proline oxidase, mitochondrial; tumor protein
Cat.#:PRODH-31088THTag:N/A
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human PRODH
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Cat.#:PRODH-326HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PRODH Protein, His-tagged
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Cat.#:PRODH-13428MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse PRODH Protein
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Cat.#:Prodh-8048MTag:His|T7
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Prodh protein, His & T7-tagged
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Cat.#:PRODH-502HCLTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human PRODH lysate
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Involved Pathway

PRODH involved in several pathways and played different roles in them. We selected most pathways PRODH participated on our site, such as Arginine and proline metabolism, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with PRODH were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Arginine and proline metabolism
PYCR1A; NOS1; SAT2; ALDH1B1; PYCR1B; ALDH18A1; GOT2; CNDP1; AMD1; ALDH4A1
Metabolic pathways
GM5506; SPRA; HAAO; GAL3ST1A; NME2B.1; IL4I1; HEXA; HMGCRB; GLCEB; CYP24A1

Protein Function

PRODH has several biochemical functions, for example, FAD binding, proline dehydrogenase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PRODH itself. We selected most functions PRODH had, and list some proteins which have the same functions with PRODH. You can find most of the proteins on our site.
Function
Related Protein
Function FAD binding
Related Protein DAO1; PRODH; KMO; DERL3; AGPS; CYB5R3; AIFM1; DDO; MICAL2B; DAO.2
Function proline dehydrogenase activity
Related Protein PRODH; PRODH2