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PRODH

Official Full Name

proline dehydrogenase (oxidase) 1
Overview

This gene encodes a mitochondrial protein that catalyzes the first step in proline degradation. Mutations in this gene are associated with hyperprolinemia type 1 and susceptibility to schizophrenia 4 (SCZD4). This gene is located on chromosome 22q11.21, a region which has also been associated with the contiguous gene deletion syndromes, DiGeorge and CATCH22. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Synonyms

PRODH; proline dehydrogenase (oxidase) 1; proline dehydrogenase (proline oxidase ); proline dehydrogenase 1, mitochondrial; HSPOX2; PIG6; PRODH1; PRODH2; TP53I6; proline oxidase 2; p53-induced gene 6 protein; proline oxidase, mitochondrial; tumor protein;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse

Source

E.coli
HEK293
Mammalian Cell
Wheat Germ

Tag

His
His (Fc)
Avi
His|T7
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	PRODH-31088TH	Recombinant Human PRODH	Wheat Germ	N/A	100 amino acids	Inquiry
Human	PRODH-326H	Recombinant Human PRODH Protein, His-tagged	E.coli	His		Inquiry
Human	PRODH-502HCL	Recombinant Human PRODH lysate	HEK293	N/A		Inquiry
Mouse	Prodh-8048M	Recombinant Mouse Prodh protein, His & T7-tagged	E.coli	His/T7	Arg398~Gly551 (Accession # Q9WU79)	Inquiry
Mouse	PRODH-13428M	Recombinant Mouse PRODH Protein	Mammalian Cell	His		Inquiry
Mouse	PRODH-7130M	Recombinant Mouse PRODH Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	PRODH-7130M-B	Recombinant Mouse PRODH Protein Pre-coupled Magnetic Beads	HEK293			Inquiry

Involved Pathway
Protein Function
Interacting Protein

PRODH involved in several pathways and played different roles in them. We selected most pathways PRODH participated on our site, such as Arginine and proline metabolism, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with PRODH were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Arginine and proline metabolism	P4HA1B;GOT1;CKMT1B;CKMA;ALDH9A1B;ABP1;DAO.1;CKMT2B;ADC
Metabolic pathways	CHIA.2;DLDH;LPIN2;ATP5D;B3GALT1;AOX1;RIMKLA;POLR3D;ASS1

PRODH has several biochemical functions, for example, FAD binding, proline dehydrogenase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PRODH itself. We selected most functions PRODH had, and list some proteins which have the same functions with PRODH. You can find most of the proteins on our site.

Function	Related Protein
FAD binding	DAO1;PRODH;CRY2;MICAL1;DAO.2;DDO;MTRR;AGPS;COQ6
proline dehydrogenase activity	PRODH2;PRODH

PRODH has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PRODH here. Most of them are supplied by our site. Hope this information will be useful for your research of PRODH.