|Official Full Name||proteasome (prosome, macropain) subunit, beta type, 4|
|Background||The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit.|
|Synonyms||PSMB4; proteasome (prosome, macropain) subunit, beta type, 4; proteasome subunit beta type-4; HN3; PROS26; hsBPROS26; proteasome chain 3; macropain beta chain; proteasome beta chain; 26 kDa prosomal protein; proteasome subunit HsN3; proteasome subunit, be|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
PSMB4 involved in several pathways and played different roles in them. We selected most pathways PSMB4 participated on our site, such as Proteasome, which may be useful for your reference. Also, other proteins which involved in the same pathway with PSMB4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Proteasome||PSMC1B; PSMB11; PSMD8; IFNG1-2; PSMB6; PSMC5; IFNG; PSMC1A; PSMB2; PSMB5|
PSMB4 has several biochemical functions, for example, endopeptidase activity, lipopolysaccharide binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PSMB4 itself. We selected most functions PSMB4 had, and list some proteins which have the same functions with PSMB4. You can find most of the proteins on our site.
|endopeptidase activity||KLK1B1; MMP3; PSMB1; TPP1; KLK1B11; TRAPPC12; PSMA4; MMP9; PSMA1; SENP1|
|lipopolysaccharide binding||KIAA0644; SPON2; TREM2; TRIL; SCARB1; TLR2; BPI; BPIFA2; PSMB4; HMGB1|
|protein binding||AVPR1A; ITGAV; OSBP2; OAS2; OAZ2; MAGEH1; CD274; TXLNG; NPM2; KIF9|
|threonine-type endopeptidase activity||PSMB8; PSMB9; PSMB4; TASP1; PRSS50; PSMA7; PSMB9A; PSMB8F; PSMA8; PSMB9B|
PSMB4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PSMB4 here. Most of them are supplied by our site. Hope this information will be useful for your research of PSMB4.
FSD2; PSMA3; UCHL5; NME2; HLA-B; HLA-C; IKBKE; MTMR10; TRAF6; PRKCA; p27958-pro_0000037577; PSMB5; SMAD1; PSMB7