Recombinant Human PSMB4, His-tagged

• Cat.No.: PSMB4-840H
• Product Overview: Recombinant Human PSMB4 was produced in E.coli with a His tag at N-terminus. MW = 29192Da (1-264aa).

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-264 a.a.
• Description: Proteasome subunit beta type-4 is a protein that in humans is encoded by the PSMB4 gene. The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit.
• Form: 10 mM Tris. pH 8.0. 0.1% Triton X-100. 0.002% NaN3. 10mM DTT.
• Purity: 95%.
• Clonality: N/A.
• Applications: MS. SDS.

Gene Information

• Gene Name: PSMB4 proteasome (prosome, macropain) subunit, beta type, 4 [ Homo sapiens ]
• Synonyms: PSMB4; proteasome (prosome, macropain) subunit, beta type, 4; HN3; HsN3; PROS26; PROS-26; proteasome subunit beta type-4; hsBPROS26; proteasome chain 3; macropain beta chain; proteasome beta chain; 26 kDa prosomal protein; proteasome subunit HsN3; proteasome subunit, beta type, 4; multicatalytic endopeptidase complex beta chain; EC 3.4.25.1
• Gene ID: 5692
• mRNA Refseq: NM_002796
• Protein Refseq: NP_002787
• MIM: 602177
• UniProt ID: P28070
• Chromosome Location: 1q21
• Pathway: Proteasome
• Function: lipopolysaccharide binding; peptidase activity; threonine-type endopeptidase activity