PSMD8 Protein, proteasome (prosome, macropain) 26S subunit, non-ATPase, 8

PSMD8

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PSMD8

Official Full Name proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
Background The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway.An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 1.
Synonyms PSMD8; proteasome (prosome, macropain) 26S subunit, non-ATPase, 8; 26S proteasome non-ATPase regulatory subunit 8; HIP6; HYPF; Nin1p; p31; Rpn12; S14; 26S proteasome non ATPase regulatory subunit 8; 26S proteasome regulatory subunit p31; 26S proteasome regulatory subunit RPN12; 26S proteasome regulatory subunit S14; AAV38494; MGC1660; Proteasome (prosome macropain) 26S subunit non ATPase 8; PSMD8_HUMAN; OTTHUMP00000198258
    • Species :
    • Human
    • Zebrafish
    • Source :
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human PSMD8-2744HCL Recombinant Human PSMD8 293 Cell Lysate HEK293 N/A
    Human PSMD8-30431TH Recombinant Human PSMD8 Wheat Germ N/A
    Zebrafish PSMD8-358Z Recombinant Zebrafish PSMD8 Mammalian Cell His

    PSMD8 involved in several pathways and played different roles in them. We selected most pathways PSMD8 participated on our site, such as Proteasome, Epstein-Barr virus infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with PSMD8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Proteasome PSME4; PSMD13; PSMF1; PSMD1; PSMC1A; PSMA1; PSMD2; PSME4B; PSMB8; PSMD4A
    Epstein-Barr virus infection GTF2B; TBK1; TP53; NFKB2; ENTPD3; HLA-DPB1; HDAC4; HLA-DRB5; MAPK11; POLR3GL

    PSMD8 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by PSMD8 itself. We selected most functions PSMD8 had, and list some proteins which have the same functions with PSMD8. You can find most of the proteins on our site.

    Function Related Protein

    PSMD8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PSMD8 here. Most of them are supplied by our site. Hope this information will be useful for your research of PSMD8.

    UCHL5; PSMD14; MCC; PSMD7; USP14; PSMD4; ARF6; PSMD6; PAAF1; PSMD13; TRAF6; SMAD9; SMAD2; Psmd14; PSMC1; ADRM1

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