ptk7
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  • Official Full Name
  • PTK7 protein tyrosine kinase 7
  • Background
  • Receptor protein tyrosine kinases transduce extracellular signals across the cell membrane. A subgroup of these kinases lack detectable catalytic tyrosine kinase activity but retain roles in signal transduction. The protein encoded by this gene is a member of this subgroup of tyrosine kinases and may function as a cell adhesion molecule. This gene is thought to be expressed in colon carcinomas but not in normal colon, and therefore may be a marker for or may be involved in tumor progression. Four transcript variants encoding four different isoforms have been found for this gene.
  • Synonyms
  • PTK7; PTK7 protein tyrosine kinase 7; inactive tyrosine-protein kinase 7; CCK4; CCK-4; colon carcinoma kinase 4; colon carcinoma kinase-4; protein-tyrosine kinase 7; tyrosine-protein kinase-like 7; pseudo tyrosine kinase receptor 7
Cat.#:PTK7-1659HTag:His
Source (Host):YeastSpecies:Human
Product nameRecombinant Human PTK7 Protein (31-704 aa), His-tagged
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Cat.#:PTK7-2108MTag:His
Source (Host):YeastSpecies:Mouse
Product nameRecombinant Mouse PTK7 Protein, His-tagged
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Cat.#:PTK7-183HTag:GST
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human PTK7, GST-tagged
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Cat.#:PTK7-27862THTag:N/A
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human PTK7
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Cat.#:PTK7-544HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PTK7 Protein, His-tagged
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Cat.#:PTK7-667HTag:DDK|His
Source (Host):HEK293 cellsSpecies:Human
Product nameRecombinant Human PTK7 Protein, DDK/His-tagged
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Cat.#:PTK7-668HTag:DDK
Source (Host):Sf9 cellsSpecies:Human
Product nameRecombinant Human PTK7 Protein, DDK-tagged
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Cat.#:PTK7-669HTag:DDK|His
Source (Host):HEK293 cellsSpecies:Human
Product nameRecombinant Human PTK7 Protein, DDK/His-tagged
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Cat.#:PTK7-670HTag:DDK|His
Source (Host):HEK293 cellsSpecies:Human
Product nameRecombinant Human PTK7 Protein, DDK/His-tagged
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Cat.#:PTK7-13660MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse PTK7 Protein
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Cat.#:PTK7-3696RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey PTK7 Protein, His-tagged
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Cat.#:PTK7-2715CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken PTK7
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Cat.#:PTK7-2697HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human PTK7 293 Cell Lysate
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Protein Function

PTK7 has several biochemical functions, for example, ATP binding, protein binding, protein tyrosine kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PTK7 itself. We selected most functions PTK7 had, and list some proteins which have the same functions with PTK7. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein CDC7; PAK2B; DDX19A; KIF3A; RFK; ABCB10; ACSM2; PEBP1; PRKG2; PANK1B
Function protein binding
Related Protein ADIPOQ; PRRG2; KLRG1; MCM10; CIB1; ADCYAP1; CTH; MAPKBP1; ZNF385C; IGSF1
Function protein tyrosine kinase activity
Related Protein LYN; MAP2K7; MAP2K3; TESK1; BMX; ERBB2; EPHA2A; SYK; DSTYK; CAMKK2

Interacting Protein

PTK7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PTK7 here. Most of them are supplied by our site. Hope this information will be useful for your research of PTK7.
CTNNB1; CLNK; prfA; wnt3a

PTK7 Related Articles

Gartner, S; Gunesch, A; et al. PTK 7 Is a Transforming Gene and Prognostic Marker for Breast Cancer and Nodal Metastasis Involvement. PLOS ONE 9:-(2014).
Zhao, WA; Cui, CH; et al. Bioinspired multivalent DNA network for capture and release of cells. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 109:19626-19631(2012).