ptpn12
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  • Official Full Name
  • protein tyrosine phosphatase, non-receptor type 12
  • Background
  • PTP-PEST is a ubiquitously expressed cytosolic protein tyrosine phosphatase with multiple proline-rich regions that appear to be the the docking sites for PTP-PEST binding partners or substrates (1). PTP-PEST regulates fibroblast adhesion, migration and c
  • Synonyms
  • PTPN12; protein tyrosine phosphatase, non-receptor type 12; tyrosine-protein phosphatase non-receptor type 12; PTP PEST; PTPG1; protein-tyrosine phosphatase G1; PTP-PEST
Cat.#:PTPN12-3135HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human PTPN12 Protein, MYC/DDK-tagged
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Cat.#:PTPN12-1620HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Protein Tyrosine Phosphatase, Non-Receptor Type 12, GST-tagged
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Cat.#:PTPN12-1909HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Protein Tyrosine Phosphatase, Non-Receptor Type 12
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Cat.#:PTPN12-411HTag:FC/His
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human PTPN12, Gly & Pro tagged
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Cat.#:PTPN12-467HTag:FC/His
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human PTPN12, His-GST tagged
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Cat.#:PTPN12-8096HTag:His/T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PTPN12 protein, His & T7-tagged
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Cat.#:PTPN12-13676MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse PTPN12 Protein
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Cat.#:PTPN12-10938ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish PTPN12
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Cat.#:PTPN12-1858HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PTPN12, GST-tagged
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Cat.#:PTPN12-462HTag:GST
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human PTPN12, GST-tagged, Active
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Cat.#:PTPN12-002HCLTag:
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human PTPN12 cell lysate
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Involved Pathway

PTPN12 involved in several pathways and played different roles in them. We selected most pathways PTPN12 participated on our site, such as EGFR1 Signaling Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with PTPN12 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
EGFR1 Signaling Pathway
RGS5B; ARF4; APPL2; PTK6; ZFP259; SH3BGRL; KRT8; REPS1; EPS8; RBB4L

Protein Function

PTPN12 has several biochemical functions, for example, SH3 domain binding, non-membrane spanning protein tyrosine phosphatase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PTPN12 itself. We selected most functions PTPN12 had, and list some proteins which have the same functions with PTPN12. You can find most of the proteins on our site.
Function
Related Protein
Function SH3 domain binding
Related Protein ARHGAP6; DNM2; FAM125A; ADAM12; USP8; ARHGAP17; SH3BP5B; SH3BGRL2; EVL; DTX1
Function non-membrane spanning protein tyrosine phosphatase activity
Related Protein PTPN4; PTPN9; ACP1; DUSP1; PTPN12; PTPN18; PTPN11
Function protein binding
Related Protein CEACAM6; ERCC8; SNAPC5; UBE2R2; MX1; MAPK11; PLCB4; IFITM3; ELF2; CECR2

Interacting Protein

PTPN12 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PTPN12 here. Most of them are supplied by our site. Hope this information will be useful for your research of PTPN12.
PDGFRB; PSTPIP1; EGFR; SHC1; WAS; BCAR1