ptpn18
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  • Official Full Name
  • protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
  • Synonyms
  • PTPN18;protein tyrosine phosphatase, non-receptor type 18 (brain-derived);9649;ENSG00000072135;BDP1;PTP-HSCF;2q21.1;tyrosine-protein phosphatase non-receptor type 18;tyrosine-protein phosphatase non-receptor type 18;brain-derived phosphatase;EC 3.1.3.48;
Cat.#:PTPN18-3132HTag:Myc|DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human PTPN18 Protein, MYC/DDK-tagged
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Cat.#:PTPN18-13679MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse PTPN18 Protein
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Cat.#:PTPN18-2142ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish PTPN18
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Cat.#:PTPN18-1437HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human PTPN18 cell lysate
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Involved Pathway

PTPN18 involved in several pathways and played different roles in them. We selected most pathways PTPN18 participated on our site, such as B Cell Receptor Signaling Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with PTPN18 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
B Cell Receptor Signaling Pathway
PDPK1A; DUSP6; RAP2A; PTPN6; MAP4K1; MALT1; CD81; DUSP4; ARPC4; FOS

Protein Function

PTPN18 has several biochemical functions, for example, non-membrane spanning protein tyrosine phosphatase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PTPN18 itself. We selected most functions PTPN18 had, and list some proteins which have the same functions with PTPN18. You can find most of the proteins on our site.
Function
Related Protein
Function non-membrane spanning protein tyrosine phosphatase activity
Related Protein PTPN9; PTPN4; PTPN11; ACP1; PTPN18; DUSP1; PTPN12
Function protein binding
Related Protein TACC3; TBC1D22B; NOA1; RUFY3; CTNNBL1; MAP3K11; PLEKHB2; SSB; HNRNPH1; CDC26

Interacting Protein

PTPN18 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PTPN18 here. Most of them are supplied by our site. Hope this information will be useful for your research of PTPN18.
PSTPIP1; EGFR; bosutinib; imatinib; SH2D1B; ABL2; GRB2

PTPN18 Related Articles

Akcakaya, P; Caramuta, S; et al. microRNA expression signatures of gastrointestinal stromal tumours: associations with imatinib resistance and patient outcome. BRITISH JOURNAL OF CANCER 111:2091-2102(2014).
Doody, KM; Bottini, N; et al. "PEST control": regulation of molecular barcodes by tyrosine phosphatases. CELL RESEARCH 24:1027-1028(2014).