rab1a
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  • Official Full Name
  • RAB1A, member RAS oncogene family
  • Background
  • This gene encodes a member of the Ras superfamily of GTPases. Members of the gene family cycle between inactive GDP-bound and active GTP-bound forms. This small GTPase controls vesicle traffic from the endoplasmic reticulum to the Golgi apparatus. Multiple alternatively spliced transcript variants have been identified for this gene which encode different protein isoforms.
  • Synonyms
  • RAB1A; RAB1A, member RAS oncogene family; RAB1; ras-related protein Rab-1A; Rab GTPase YPT1 homolog (yeast); YPT1; DKFZP564B163; GTP binding protein RAB 1A; GTP Binding Protein RAB1A; RAB 1; Rab 1A; RAB1, member RAS oncogene family; RAB1A member RAS oncogene family; RAB1A_HUMAN; Ras related protein Rab 1A; Ras-associated protein RAB1; YPT1 related protein; YPT1-related protein; Rab GTPase YPT1 homolog
Cat.#:RAB1A-2104HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human RAB1A, GST-tagged
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Cat.#:RAB1A-3470HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human RAB1A, His-tagged
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Cat.#:RAB1A-705MTag:GST/His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse RAB1A Protein, GST/His-tagged
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Cat.#:RAB1A-3736RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey RAB1A Protein, His-tagged
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Cat.#:RAB1A-4650CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken RAB1A
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Cat.#:RAB1A-1651ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish RAB1A
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Cat.#:RAB1A-2623HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human RAB1A 293 Cell Lysate
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Involved Pathway

RAB1A involved in several pathways and played different roles in them. We selected most pathways RAB1A participated on our site, such as Legionellosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with RAB1A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Legionellosis
NFKB2; IL-8; BCL2L13; RAB1A; SAR1A; MYD88; ITGB2L; CYCS; TLR4; HSPA8

Protein Function

RAB1A has several biochemical functions, for example, GTP binding, GTPase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RAB1A itself. We selected most functions RAB1A had, and list some proteins which have the same functions with RAB1A. You can find most of the proteins on our site.
Function
Related Protein
Function GTP binding
Related Protein RASL11B; IRGF4; RHOGD; REM1; GBP2; ARF1L; RIT2; ASCL1B; RAB32A; MMAA
Function GTPase activity
Related Protein GBP4; RAB13; RRAGC; RAB42A; EEF2A.2; RAB44; MTG1; RAB14L; RAB1BB; RAB39A
Function protein binding
Related Protein GGACT; INIP; STX16; RND2; SIAH2; FAM193B; PIANP; SNAP91; KRTAP5-6; PPP1R37

Interacting Protein

RAB1A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RAB1A here. Most of them are supplied by our site. Hope this information will be useful for your research of RAB1A.
drrA; gtp; OCRL

RAB1A Related Articles

Tanaka, M; Mun, S; et al. Hsc70 Contributes to Cancer Cell Survival by Preventing Rab1A Degradation under Stress Conditions. PLOS ONE 9:-(2014).
Zenner, HL; Yoshimura, S; et al. Analysis of Rab GTPase-Activating Proteins Indicates that Rab1a/b and Rab43 Are Important for Herpes Simplex Virus 1 Secondary Envelopment. JOURNAL OF VIROLOGY 85:8012-8021(2011).