rars
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  • Official Full Name
  • arginyl-tRNA synthetase
  • Background
  • Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Arginyl-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family.
  • Synonyms
  • RARS; arginyl-tRNA synthetase; arginine--tRNA ligase, cytoplasmic; arginine tRNA ligase 1; cytoplasmic; DALRD1; arginine tRNA ligase 1, cytoplasmic; arginyl-tRNA synthetase, cytoplasmic; ArgRS; MGC8641
Cat.#:RARS-26535THTag:
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human RARS
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Cat.#:RARS-8207HTag:His/T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human RARS protein, His & T7-tagged
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Cat.#:RARS-13937MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse RARS Protein
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Cat.#:Rars-3623RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat Rars, His-tagged
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Cat.#:RARS-4929RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat RARS Protein
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Cat.#:RARS-3791RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey RARS Protein, His-tagged
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Cat.#:RARS-2319CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken RARS
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Cat.#:RARS-10403ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish RARS
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Cat.#:RARS-1472HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human RARS cell lysate
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Involved Pathway

RARS involved in several pathways and played different roles in them. We selected most pathways RARS participated on our site, such as Aminoacyl-tRNA biosynthesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with RARS were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Aminoacyl-tRNA biosynthesis
HARS; GATB; VARS2; RARS; DARS2; IARS; VARS; FARSA; SEPSECS; SARS

Protein Function

RARS has several biochemical functions, for example, ATP binding, arginine binding, arginine-tRNA ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by RARS itself. We selected most functions RARS had, and list some proteins which have the same functions with RARS. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein DAPK1; DDX39; HELB; PAK4; Ckmm; EPHB4; NAIP7; TPX2; ERCC6; ACTA2
Function arginine binding
Related Protein NAGS; NOS3; NOS2; NOS1; RARS
Function arginine-tRNA ligase activity
Related Protein RARS2; RARS; DALRD3
Function protein binding
Related Protein MX2; CAB39; FDX1L; TBX5A; CCDC9; LRRFIP2; NSF; TSKS; ADRB1; TMEM41A
Function tRNA binding
Related Protein XPO5; NSUN2; KARS; AARS; TRMU; ALKBH8; MADD; IGHMBP2; IFIT5; EEF1A1

Interacting Protein

RARS has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RARS here. Most of them are supplied by our site. Hope this information will be useful for your research of RARS.
LARS; gag; NFKBIE; TNFRSF1A; HLA-B; NFKB2; CBFB; IKBKE; RNPS1; TANK; MAP3K14; IKBKG; EPRS; 15-deoxy-delta(12,14; midostaurin; ssrna_ug

RARS Related Articles

Miyabe, Y; Miyabe, C; et al. Could retinoids be a potential treatment for rheumatic diseases?. RHEUMATOLOGY INTERNATIONAL 35:35-41(2015).
Buchanan, FQ; Rochette-Egly, C; et al. Detection of variable levels of RAR alpha and RAR gamma proteins in pluripotent and differentiating mouse embryonal carcinoma and mouse embryonic stem cells. CELL AND TISSUE RESEARCH 346:43-51(2011).