rgs21
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  • Official Full Name
  • regulator of G-protein signaling 21
  • Background
  • Regulator of G protein signaling (RGS) proteins are regulatory and structural components of G protein-coupled receptor complexes. RGS proteins are GTPase-activating proteins for Gi (see GNAI1; MIM 139310) and Gq (see GNAQ; MIM 600998) class G-alpha proteins. They accelerate transit through the cycle of GTP binding and hydrolysis and thereby accelerate signaling kinetics and termination.
  • Synonyms
  • RGS21; regulator of G-protein signaling 21; regulator of G protein signalling 21; regulator of G-protein signalling 21
Cat.#:RGS21-3615HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human RGS21, His-tagged
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Cat.#:RGS21-29966THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human RGS21, His-tagged
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Involved Pathway

RGS21 involved in several pathways and played different roles in them. We selected most pathways RGS21 participated on our site, such as G alpha (i) signalling events, G alpha (q) signalling events, GPCR downstream signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with RGS21 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
G alpha (i) signalling events
HRH3; PYYA; LPAR2A; NMS; HEBP1; OPN1MW2; RGR; ANXA1B; RGS12; NMUR1
G alpha (q) signalling events
ABHD6B; OXTRL; NMBA; MGLL; KISS1; TRH; RGS19; ARHGEF25; ANXA1B; NPSR1
GPCR downstream signaling
SSTR2; GRP; GHRH; ABR; ADRA2C; ITSN1; RGS21; CHRM2; PTH2; ABHD12
Gastrin-CREB signalling pathway via PKC and MAPK
TAC2; NMU; CCK; LTB4R; NMBB; GPR65; OPN4B; KISS1; QRFPR; NMUR1
Signal Transduction
DHRS4; RSPO3; FAM13A; ARHGAP26; RYK; CBY1; EDNRAB; FSTB; UCHL5; NOXO1
Signaling by GPCR
RAMP3; PENK; RGS20; CNR2; ANXA1B; OXGR1A.3; CCBP2; ACKR4; ARHGEF1B; ARHGAP4

Protein Function

RGS21 has several biochemical functions, for example, GTPase activator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by RGS21 itself. We selected most functions RGS21 had, and list some proteins which have the same functions with RGS21. You can find most of the proteins on our site.
Function
Related Protein
Function GTPase activator activity
Related Protein RGS4; ARHGAP5; RASAL1; JUN; PLCB1; RANGAP1B; RALGAPA2; GMIP; ARHGAP15; USP6NL