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RIN2

  • Official Full Name

    RAB5 interacting protein 2

  • Overview

    The RAB5 protein is a small GTPase involved in membrane trafficking in the early endocytic pathway. The protein encoded by this gene binds the GTP-bound form of the RAB5 protein preferentially over the GDP-bound form, and functions as a guanine nucleotide exchange factor for RAB5. The encoded protein is found primarily as a tetramer in the cytoplasm and does not bind other members of the RAB family. Mutations in this gene cause macrocephaly alopecia cutis laxa and scoliosis (MACS) syndrome, an elastic tissue disorder, as well as the related connective tissue disorder, RIN2 syndrome. Alternative splicing results in multiple transcript variants.
  • Synonyms

    RIN2; RAB5 interacting protein 2;
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human RIN2-722H Recombinant Human RIN2 Protein, GST-tagged E.coli GST
Human RIN2-1347H Recombinant Human RIN2 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human RIN2-1040H Recombinant Human RIN2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Mouse Rin2-5517M Recombinant Mouse Rin2 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Arabidopsis thaliana (Mouse-ear cress) RFL19022AF Recombinant Full Length Arabidopsis Thaliana E3 Ubiquitin Protein Ligase Rin2(Rin2) Protein, His-Tagged E.coli expression system His Full Length (1-578)

RIN2 involved in several pathways and played different roles in them. We selected most pathways RIN2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with RIN2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

RIN2 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by RIN2 itself. We selected most functions RIN2 had, and list some proteins which have the same functions with RIN2. You can find most of the proteins on our site.

Function Related Protein

RIN2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RIN2 here. Most of them are supplied by our site. Hope this information will be useful for your research of RIN2.

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