"RIN2" Related Products

Recombinant Human RIN2 Protein, GST-tagged

Cat.No. : RIN2-722H
Product Overview : Recombinant Human RIN2 protein (residues (785-879) ) was expressed in E. coli with GST tag.
Description : RIN2, only expressed in neurons, preferentially interacts with the GTP form of Rab5 rather than the GDP form, although it enhances the guanine exchange reaction on Rab5. Moreover, gel filtration and immunoprecipitation analyses suggest that RIN2 could form a tetramer composed of anti-parallel linkage of two parallel dimers. These results suggest that RIN2 may function as an upstream activator and/or downstream effector for Rab5 in the endocytic pathway. Additionally RIN2 interacts with several Ras proteins, it binds the GTP-loaded forms of H-Ras, TC21 and M-Ras.
Source : E. coli
Species : Human
Tag : GST
Form : 25 mM HEPES pH 7.5, 50 mM NaCl, 1 mM EDTA and 50% glycerol
Purity : > 95 % (SDS-PAGE)
Storage : Store at -20 centigrade, avoid freeze/thaw cycles.
Gene Name : RIN2 RAB5 interacting protein 2 [ Homo sapiens ]
Official Symbol : RIN2
Synonyms : MACS; RASSF4
Gene ID : 54453
mRNA Refseq : NM_018993
Protein Refseq : NP_061866
MIM : 610222
UniProt ID : Q8WYP3

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