rnf125
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  • Official Full Name
  • ring finger protein 125, E3 ubiquitin protein ligase
  • Background
  • This gene encodes a novel E3 ubiquitin ligase that contains an N-terminal RING finger domain. The encoded protein may function as a positive regulator in the T-cell receptor signaling pathway.
  • Synonyms
  • RNF125; ring finger protein 125, E3 ubiquitin protein ligase; ring finger protein 125; E3 ubiquitin-protein ligase RNF125; FLJ20456; T-cell RING activation protein 1; T-cell ring protein identified in activation screen; TRAC1; TRAC-1; MGC21737
Cat.#:RNF125-14294MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse RNF125 Protein
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Cat.#:RNF125-859CTag:His
Source (Host):Mammalian CellsSpecies:Cynomolgus Monkey
Product nameRecombinant Cynomolgus RNF125 Protein, His-tagged
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Cat.#:RNF125-545HCLTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human RNF125 lysate
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Involved Pathway

RNF125 involved in several pathways and played different roles in them. We selected most pathways RNF125 participated on our site, such as RIG-I-like receptor signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with RNF125 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
RIG-I-like receptor signaling pathway
IFNK; PIN1; TRADD; NLRX1; IL12B; ATG5; IFNB1; IL12A; SIKE1; IFNA8

Protein Function

RNF125 has several biochemical functions, for example, ligase activity, ubiquitin-protein transferase activity, zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RNF125 itself. We selected most functions RNF125 had, and list some proteins which have the same functions with RNF125. You can find most of the proteins on our site.
Function
Related Protein
Function ligase activity
Related Protein NEDD4L; FANCL; UBE2KA; LRSAM1; BIRC2; DTX3L; BRAP; RNF144AA; RNF13; UBE2KB
Function ubiquitin-protein transferase activity
Related Protein TRIM17; TRAF4A; UHRF1; AMFR; MARCH6; NEDD4L; ZNRF3; FBXO9; MARCH5; BTR22
Function zinc ion binding
Related Protein TRAF6; TMEM163; MT1E; LNPEP; THRA; PHF23B; TRIM13; RARGB; MEP1A; ADAM10A

Interacting Protein

RNF125 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RNF125 here. Most of them are supplied by our site. Hope this information will be useful for your research of RNF125.
UBE2L6; UBE2L3; HIP2; PML; UBE2D1; UBE2D3; UBE2K; UBE2N; UBE2D2; prfA; UBE2U; TRIM46; UBE2W; CHFR; UBE2E2; PCGF1; UBE2D4