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RNF125

Official Full Name

ring finger protein 125, E3 ubiquitin protein ligase
Overview

This gene encodes a novel E3 ubiquitin ligase that contains an N-terminal RING finger domain. The encoded protein may function as a positive regulator in the T-cell receptor signaling pathway.
Synonyms

RNF125; ring finger protein 125, E3 ubiquitin protein ligase; ring finger protein 125; E3 ubiquitin-protein ligase RNF125; FLJ20456; T-cell RING activation protein 1; T-cell ring protein identified in activation screen; TRAC1; TRAC-1; MGC21737;

Type

Cell & Tissue Lysates
Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Cynomolgus Monkey
Human
Mouse

Source

E.coli
HEK293
Mammalian Cell

Tag

GST
His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	RNF125-545HCL	Recombinant Human RNF125 lysate	HEK293	N/A		Inquiry
Human	RNF125-2119H	Recombinant Human RNF125 Protein (1-232 aa), GST-tagged	E.coli	GST	1-232 aa	Inquiry
Human	RNF125-2646H	Recombinant Human RNF125 protein, His-tagged	E.coli	His	1 - 232 aa	$319 / 25ug
Mouse	RNF125-14294M	Recombinant Mouse RNF125 Protein	Mammalian Cell	His		Inquiry
Mouse	RNF125-7647M	Recombinant Mouse RNF125 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	RNF125-7647M-B	Recombinant Mouse RNF125 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Cynomolgus Monkey	RNF125-859C	Recombinant Cynomolgus RNF125 Protein, His-tagged	Mammalian Cell	His		Inquiry
Cynomolgus Monkey	RNF125-602C	Recombinant Cynomolgus Monkey RNF125 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Cynomolgus Monkey	RNF125-602C-B	Recombinant Cynomolgus Monkey RNF125 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry

Involved Pathway
Protein Function
Interacting Protein

RNF125 involved in several pathways and played different roles in them. We selected most pathways RNF125 participated on our site, such as RIG-I-like receptor signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with RNF125 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
RIG-I-like receptor signaling pathway	NT5C3;PIN1;RIPK1;CASP10;NFKBIB;IFNA14;MAPK12A;MAP3K1;IL12B

RNF125 has several biochemical functions, for example, ligase activity, ubiquitin-protein transferase activity, zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RNF125 itself. We selected most functions RNF125 had, and list some proteins which have the same functions with RNF125. You can find most of the proteins on our site.

Function	Related Protein
ligase activity	TRIM17;RNF123;PRP19;C12orf51;RNF220;MARCH9;BIRC3;SIAH1;MARCH6
ubiquitin-protein transferase activity	ITCHA;TRAF6;MARCH8;NEDD4L;UBE2L3;BIRC3;BIRC8;HECTD3;CBL
zinc ion binding	LIMK2;PDXK;LHX3;CBL;NEIL2;BRD1;LMO1;ADAMTS5;NEURL1AB

RNF125 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RNF125 here. Most of them are supplied by our site. Hope this information will be useful for your research of RNF125.

UBE2L6; UBE2L3; HIP2; PML; UBE2D1; UBE2D3; UBE2K; UBE2N; UBE2D2; prfA; UBE2U; TRIM46; UBE2W; CHFR; UBE2E2; PCGF1; UBE2D4