RNF181
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Official Full Name
ring finger protein 181
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Overview
RNF181 binds the integrin alpha-IIb (ITGA2B; MIM 607759)/beta-3 (ITGB3; MIM 173470) complex and has E3 ubiquitin ligase activity (Brophy et al., 2008 -
Synonyms
RNF181; ring finger protein 181; E3 ubiquitin-protein ligase RNF181; HSPC238; 2500002L14Rik; 6230415N01Rik; C77350; MGC103058; OTTHUMP00000209531; OTTHUMP00000209532; 1700047F16Rik; E3 ubiquitin protein ligase RNF181; LOC51255; MGC94464; RN181; OTTHUMP00000160685;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- Rhesus Macaque
- Zebrafish
- E.coli
- HEK293
- HEK293T
- Mammalian Cell
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- Myc|DDK
- N/A
- No tag
- Involved Pathway
- Protein Function
- Interacting Protein
RNF181 involved in several pathways and played different roles in them. We selected most pathways RNF181 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with RNF181 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
RNF181 has several biochemical functions, for example, ligase activity, ubiquitin protein ligase activity, ubiquitin-protein transferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by RNF181 itself. We selected most functions RNF181 had, and list some proteins which have the same functions with RNF181. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ligase activity | MGRN1;TRIM58;RAD18;SYVN1;HECW1;DTX3L;RNF130;RC3H2;RNF4 |
| ubiquitin protein ligase activity | HECW2;HECTD3;FBXO6;RNF121;UBE2G1A;UBE2R2;FBXO40;HACE1;UBE2C |
| ubiquitin-protein transferase activity | RBBP6;RNF144AB;FLJ11011L;MUL1;MDM2;ZNRF3;PARK2;FBXL21;UBR1 |
| zinc ion binding | MSRB3;RXRG;KAT7B;GATAD2AB;ZRANB3;UNK;FBXO30B;SPG7;SAMHD1 |
RNF181 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RNF181 here. Most of them are supplied by our site. Hope this information will be useful for your research of RNF181.
TRIM24; ZMYND10; UBE2D1; UBE2E1; UBE2D3; BTG1; UBE2D2; MRPS6; BIRC2; NPY5R; UBE2U; PEG10; UBE2E3; RBCK1; TRIM8; VPS11; CLK4; UBE2D4; SHFM1
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