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Rnf5

  • Official Full Name

    ring finger protein 5, E3 ubiquitin protein ligase

  • Overview

    The protein encoded by this gene contains a RING finger, which is a motif known to be involved in protein-protein interactions. This protein is a membrane-bound ubiquitin ligase. It can regulate cell motility by targeting paxillin ubiquitination and altering the distribution and localization of paxillin in cytoplasm and cell focal adhesions.
  • Synonyms

    RNF5; RMA1; RING5; ring finger protein 5, E3 ubiquitin protein ligase; E3 ubiquitin-protein ligase RNF5; protein G16; ram1 homolog;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Rat
  • Rattus norvegicus (Rat)
  • Rhesus Macaque
  • E.coli
  • E.coli expression system
  • HEK293
  • In vitro E. coli expression system
  • Mammalian Cell
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human RNF5-609H Recombinant Human RNF5 Mammalian Cell His
Human RNF5-2347H Recombinant Human RNF5, GST-tagged E.coli GST 1-125aa
Human RNF5-549HCL Recombinant Human RNF5 lysate HEK293 N/A
Human RNF5-4520H Recombinant Human RNF5 Full Length Transmembrane protein, His-tagged In vitro E. coli expression system His 2-180aa
Human RNF5-3996H Recombinant Human RNF5 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human RNF5-3996H-B Recombinant Human RNF5 Protein Pre-coupled Magnetic Beads HEK293
Mouse RNF5-14352M Recombinant Mouse RNF5 Protein Mammalian Cell His
Mouse RNF5-7688M Recombinant Mouse RNF5 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse RNF5-7688M-B Recombinant Mouse RNF5 Protein Pre-coupled Magnetic Beads HEK293
Rat RNF5-5086R Recombinant Rat RNF5 Protein Mammalian Cell His
Rat RNF5-4745R Recombinant Rat RNF5 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat RNF5-4745R-B Recombinant Rat RNF5 Protein Pre-coupled Magnetic Beads HEK293
Homo sapiens (Human) RFL26777HF Recombinant Full Length Human E3 Ubiquitin-Protein Ligase Rnf5(Rnf5) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (2-180aa)
Mus musculus (Mouse) RFL18318MF Recombinant Full Length Mouse E3 Ubiquitin-Protein Ligase Rnf5(Rnf5) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (2-180)
Rattus norvegicus (Rat) RFL13426RF Recombinant Full Length Rat E3 Ubiquitin-Protein Ligase Rnf5(Rnf5) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (2-180)
Rhesus Macaque RNF5-3946R Recombinant Rhesus monkey RNF5 Protein, His-tagged Mammalian Cell His
Rhesus Macaque RNF5-3763R-B Recombinant Rhesus Macaque RNF5 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque RNF5-3763R Recombinant Rhesus Macaque RNF5 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Rnf5 Related Articles
  • Rnf5 Related Research Area

Rnf5 involved in several pathways and played different roles in them. We selected most pathways Rnf5 participated on our site, such as Protein processing in endoplasmic reticulum, which may be useful for your reference. Also, other proteins which involved in the same pathway with Rnf5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Protein processing in endoplasmic reticulumHSP90AA1;SEC13;UBE2D2A;ERP29;HSPA6;HSPA5;UBE2D4;MAPK8A;UFD1L

Rnf5 has several biochemical functions, for example, ligase activity, protein binding, ubiquitin protein ligase activity involved in ERAD pathway. Some of the functions are cooperated with other proteins, some of the functions could acted by Rnf5 itself. We selected most functions Rnf5 had, and list some proteins which have the same functions with Rnf5. You can find most of the proteins on our site.

Function Related Protein
ligase activityCNOT4;CBLB;BIRC2;BIRC3;MUL1A;RNF38;NAPRT1;TRIM13;FPGS
protein bindingCTPS2;GTF2H2C_2;MAB21L3;TOB1A;DDX39A;KIF1C;PEG10;SMCO4;PLAT
ubiquitin protein ligase activity involved in ERAD pathwayTMEM129;SYVN1;RNF5;AMFR;TRIM25;RNF185;STUB1;PARK2
ubiquitin-protein transferase activityMKRN1;DTX3L;MARCH5;BIRC7;FBXO3;FBXO7;UBE2H;PRP19;UBR3
zinc ion bindingZBTB32;NEIL2;HIF1AN;ADH1;RNF215;TAF15;ZNF259;LIMS1;LIMS2

Rnf5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Rnf5 here. Most of them are supplied by our site. Hope this information will be useful for your research of Rnf5.

UBE2D3; UBE2E3; UBE2D1; UBE2E2

Qin, Y; Zhou, MT; et al. RNF26 Temporally Regulates Virus-Triggered Type I Interferon Induction by Two Distinct Mechanisms. PLOS PATHOGENS 10:-(2014).
Bernasconi, R; Galli, C; et al. Autoadaptive ER-Associated Degradation Defines a Preemptive Unfolded Protein Response Pathway. MOLECULAR CELL 52:783-793(2013).
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