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ROBO2

  • Official Full Name

    roundabout, axon guidance receptor, homolog 2 (Drosophila)

  • Overview

    The protein encoded by this gene belongs to the ROBO family, part of the immunoglobulin superfamily of proteins that are highly conserved from fly to human. The encoded protein is a transmembrane receptor for the slit homolog 2 protein and functions in axon guidance and cell migration. Mutations in this gene are associated with vesicoureteral reflux, characterized by the backward flow of urine from the bladder into the ureters or the kidney. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]
  • Synonyms

    ROBO2; roundabout, axon guidance receptor, homolog 2 (Drosophila); SAX3; roundabout homolog 2;

  • Cell & Tissue Lysates
  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Zebrafish
  • HEK293
  • HEK293T
  • Human Cell
  • Mammalian Cell
  • Mammalian cells
  • C
  • His
  • Flag
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human ROBO2-1225HCL Recombinant Human ROBO2 cell lysate Human Cell N/A
Human ROBO2-1903H Recombinant Human ROBO2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human ROBO2-674HFL Recombinant Full Length Human ROBO2 Protein, C-Flag-tagged Mammalian cells Flag
Human ROBO2-2779H Recombinant Human ROBO2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human ROBO2-1903H-B Recombinant Human ROBO2 Protein Pre-coupled Magnetic Beads HEK293
Human ROBO2-3268H Recombinant Human ROBO2 protein(Met1-Pro859), His-tagged HEK293 C-His Met1-Pro859
Mouse Robo2-5567M Recombinant Mouse Robo2 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Zebrafish ROBO2-9171Z Recombinant Zebrafish ROBO2 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • ROBO2 Related Research Area

ROBO2 involved in several pathways and played different roles in them. We selected most pathways ROBO2 participated on our site, such as Axon guidance, which may be useful for your reference. Also, other proteins which involved in the same pathway with ROBO2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Axon guidanceNRP2;NRG4;SEMA3A;SEMA3G;CAP2;PHB;NRG3;EFNB3B;ABLIM1

ROBO2 has several biochemical functions, for example, axon guidance receptor activity, identical protein binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ROBO2 itself. We selected most functions ROBO2 had, and list some proteins which have the same functions with ROBO2. You can find most of the proteins on our site.

Function Related Protein
axon guidance receptor activityROBO2;EPHB3;GFRA3;SEMA5A;EPHA7;EPHB1;ROBO1
identical protein bindingTOPBP1;ERBB2;PIK3AP1;TYSND1;NLRC4;ESYT2;FGFR1;PCNA;DACT3
protein bindingNPHS1;GLS;ATRNL1;BCAM;PNMA1;EPHA7;MS4A1;FER;NME1

ROBO2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ROBO2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ROBO2.

Dlg4; ROBO1; BNIP3L; RPS6KA5; OLFM2; HLA-DPB1; CPE; NR4A1; NR1H2; SSRP1; CENPU; yheI; KCNRG; RDH11; UBQLN4; PPP1R1B; KIF2A; KIF1C; MYC

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