scn2b
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  • Official Full Name
  • sodium channel, voltage-gated, type II, beta
  • Background
  • forms a voltage gated sodium channel with alpha subunit; may modulate sodium channel expression in neurons
  • Synonyms
  • SCN2B; sodium channel, voltage-gated, type II, beta; sodium channel subunit beta-2; Neuronal voltage gated sodium channel beta 2 subunit; Scn 2b; SCN2B_HUMAN; Sodium channel beta 2 subunit; Sodium channel subunit beta 2; Sodium channel voltage gated type II beta; Sodium channel voltage gated type II beta polypeptide; Sodium channel beta 2; sodium channel, voltage-gated, type II, beta polypeptide; SCNB2
Cat.#:SCN2B-2536HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human SCN2B, GST-tagged
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Cat.#:SCN2B-310HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human SCN2B, His tagged
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Cat.#:SCN2B-31351THTag:N/A
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human SCN2B
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Cat.#:SCN2B-697HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human SCN2B Protein, His-tagged
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Cat.#:SCN2B-8616HTag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human SCN2B, Fc tagged
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Cat.#:SCN2B-5263RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat SCN2B Protein
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Cat.#:SCN2B-4100RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey SCN2B Protein, His-tagged
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Cat.#:SCN2B-4815ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish SCN2B
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Cat.#:SCN2B-1280HCLTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human SCN2B cell lysate
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Cat.#:SCN2B-975HCLTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human SCN2B cell lysate
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Involved Pathway

SCN2B involved in several pathways and played different roles in them. We selected most pathways SCN2B participated on our site, such as Axon guidance, Developmental Biology, Interaction between L1 and Ankyrins, which may be useful for your reference. Also, other proteins which involved in the same pathway with SCN2B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Axon guidance
TRIO; MYL12B; PLXNA3; Ntng2; DUSP10; RGS3; PPP3R2; TRPC4; SEMA4B; ARPC5
Developmental Biology
SPTB; NADL1.1; TRIO; EFNB3B; ARPC5; COL9A1B; TRPC7; ANK2B; KIF4; ACVR1C
Interaction between L1 and Ankyrins
SCN3B; SCN8A; ANK2B; SCN3A; SCN9A; SCN2B; SCN4A; NADL1.1; KCNQ3; SCN2A
L1CAM interactions
NRP1A; SCN4A; KCNQ2; SCN3A; RANBP9; KCNQ3; CNTN1; SCN2A; CHL1; KIF4

Protein Function

SCN2B has several biochemical functions, for example, sodium channel regulator activity, voltage-gated sodium channel activity involved in cardiac muscle cell action potential. Some of the functions are cooperated with other proteins, some of the functions could acted by SCN2B itself. We selected most functions SCN2B had, and list some proteins which have the same functions with SCN2B. You can find most of the proteins on our site.
Function
Related Protein
Function sodium channel regulator activity
Related Protein FXYD4; SGK2B; PKP2; NEDD4L; SGK1; PTPN3; FGF12; SGK2A; SCN3B; GPD1L
Function voltage-gated sodium channel activity involved in cardiac muscle cell action potential
Related Protein SCN3B; SCN5A; SCN2B; SCN1B

SCN2B Related Articles

Szpyt, J; Lorenzon, N; et al. Three-Dimensional Localization of the alpha and beta Subunits and of the II-III Loop in the Skeletal Muscle L-type Ca2+ Channel. JOURNAL OF BIOLOGICAL CHEMISTRY 287:43853-43861(2012).
Whitaker, WRJ; Faull, RLM; et al. Comparative distribution of voltage-gated sodium channel proteins in human brain. MOLECULAR BRAIN RESEARCH 88:37-53(2001).