sema3b
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  • Official Full Name
  • sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
  • Background
  • The protein encoded by this gene belongs to the class-3 semaphorin/collapsin family, whose members function in growth cone guidance during neuronal development. This family member inhibits axonal extension and has been shown to act as a tumor suppressor by inducing apoptosis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2014]
  • Synonyms
  • SEMA3B; sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B; SemA; SEMA5; SEMAA; semaV; LUCA-1; semaphorin-3B; sema A(V); semaphorin A; semaphorin-V;
Cat.#:SEMA3B-251HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human SEMA3B protein, GST-tagged
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Cat.#:Sema3b-616MTag:Fc
Source (Host):NSO CellsSpecies:Mouse
Product nameRecombinant Mouse Sema3b Protein, Fc Chimera
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Cat.#:SEMA3B-6858ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish SEMA3B
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Cat.#:SEMA3B-1981HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human SEMA3B 293 Cell Lysate
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Involved Pathway

SEMA3B involved in several pathways and played different roles in them. We selected most pathways SEMA3B participated on our site, such as Axon guidance, which may be useful for your reference. Also, other proteins which involved in the same pathway with SEMA3B were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Axon guidance
AKAP9; CSK; EPHA4A; DPYSL5A; NTN1; NRP1; DCC; TRPC5; CSNK2A1; ITGB1B.1

Protein Function

SEMA3B has several biochemical functions, for example, chemorepellent activity, neuropilin binding, semaphorin receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SEMA3B itself. We selected most functions SEMA3B had, and list some proteins which have the same functions with SEMA3B. You can find most of the proteins on our site.
Function
Related Protein
Function chemorepellent activity
Related Protein EPHA7; NRG3; SEMA6E; SEMA3AA; SEMA6DL; SEMA4C; SEMA3B; SEMA4BA; Sema3f; SEMA6D
Function neuropilin binding
Related Protein SEMA4E; SEMA3G; SEMA7A; SEMA3FA; SEMA3BL; SEMA3D; SEMA3H; SEMA3AB; SEMA3A; Sema3f
Function semaphorin receptor binding
Related Protein SEMA3AB; SEMA6A; SEMA5A; SEMA4BA; SEMA3BL; SEMA4D; SEMA5B; SEMA6D; SEMA3C; SEMA3FA

Interacting Protein

SEMA3B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SEMA3B here. Most of them are supplied by our site. Hope this information will be useful for your research of SEMA3B.
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