SETD3 Protein, SET domain containing 3


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Official Full Name SET domain containing 3
Synonyms SETD3; SET domain containing 3; C14orf154, chromosome 14 open reading frame 154; histone-lysine N-methyltransferase setd3; FLJ23027; SET domain-containing protein 3; C14orf154; MGC87236; DKFZp761E1415
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Tag :
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human SETD3-01H Recombinant Human SETD3 Protein, His-tagged E.coli His
    Human SETD3-1927HCL Recombinant Human SETD3 293 Cell Lysate HEK293 N/A
    Human SETD3-30077TH Recombinant Human SETD3, His-tagged E.coli His
    Mouse SETD3-14980M Recombinant Mouse SETD3 Protein Mammalian Cell His
    Rhesus Macaque SETD3-4163R Recombinant Rhesus monkey SETD3 Protein, His-tagged Mammalian Cell His
    Chicken SETD3-1625C Recombinant Chicken SETD3 Mammalian Cell His
    Zebrafish SETD3-10409Z Recombinant Zebrafish SETD3 Mammalian Cell His

    SETD3 involved in several pathways and played different roles in them. We selected most pathways SETD3 participated on our site, such as Chromatin modifying enzymes, Chromatin organization, PKMTs methylate histone lysines, which may be useful for your reference. Also, other proteins which involved in the same pathway with SETD3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Chromatin modifying enzymes ING5; KDM4C; ARID2; MORF4L1; ELP3; MSL3; COPRS; CARM1; PHF8; KAT7B
    Chromatin organization KIAA1267; KANSL3; KDM4C; PADI4; C3orf75; SMARCA2; DNMT3A; ING3; PADI2; KDM5A
    PKMTs methylate histone lysines PRDM16; RBBP5; EED; SMYD2; SMYD3; SETD3; ATF7IP; SUZ12B; AEBP2; SMYD2A

    SETD3 has several biochemical functions, for example, RNA polymerase II activating transcription factor binding, histone methyltransferase activity (H3-K36 specific), histone methyltransferase activity (H3-K4 specific). Some of the functions are cooperated with other proteins, some of the functions could acted by SETD3 itself. We selected most functions SETD3 had, and list some proteins which have the same functions with SETD3. You can find most of the proteins on our site.

    Function Related Protein
    RNA polymerase II activating transcription factor binding HIPK2; NFE2L2; EP300; EGR2; T; CREB1; HNF4A; NEUROD1; HEY2; LMO2
    histone methyltransferase activity (H3-K36 specific) SMYD2B; SETD3; SMYD2; NSD1; SETMAR; ASH1L; SETD2; SMYD2A
    histone methyltransferase activity (H3-K4 specific) KMT2E; WHSC1L1; MLL1; ASH1L; WBP7; SMYD1B; MLL5; SETMAR; SETD3; WDR82
    transcription coactivator activity UTF1; ATF2; PCBD1; SUPT3H; ESR2; SRA1; SNW1; TRIP4; JUPA; JUNBA

    SETD3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SETD3 here. Most of them are supplied by our site. Hope this information will be useful for your research of SETD3.

    SRPK1; 1-phosphatidyl-1d-myo-inositol 3,5-bisphosphate; cona_canen

    Elf, K; Sheuchenko, G; et al. Alterations in muscle proteome of patients diagnosed with amyotrophic lateral sclerosis. JOURNAL OF PROTEOMICS 108:55-64(2014).
    Fabi, A; Mottolese, M; et al. Therapeutic targeting of ERBB2 in breast cancer: understanding resistance in the laboratory and combating it in the clinic. JOURNAL OF MOLECULAR MEDICINE-JMM 92:681-695(2014).

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