setd6
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  • Official Full Name
  • SET domain containing 6
  • Synonyms
  • SETD6; SET domain containing 6; N-lysine methyltransferase SETD6; FLJ21148; SET domain-containing protein 6
Cat.#:SETD6-1002HTag:Myc|DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human SETD6 Protein, MYC/DDK-tagged
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Cat.#:SETD6-200HTag:GST
Source (Host):Insect cellsSpecies:Human
Product nameRecombinant Human SETD6 protein, GST-tagged, Active
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Cat.#:SETD6-261HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human SETD6 protein, GST-tagged
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Cat.#:SETD6-14983MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse SETD6 Protein
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Cat.#:SETD6-5349RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat SETD6 Protein
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Cat.#:SETD6-2277CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken SETD6
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Cat.#:SETD6-10003ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish SETD6
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Involved Pathway

SETD6 involved in several pathways and played different roles in them. We selected most pathways SETD6 participated on our site, such as Activation of SMO, Assembly of the primary cilium, BBSome-mediated cargo-targeting to cilium, which may be useful for your reference. Also, other proteins which involved in the same pathway with SETD6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Activation of SMO
CDON; SETD6; CSNK1A1; EVC; EFCAB7; IQCE; BOC; ADRBK1; GAS8; EVC2
Assembly of the primary cilium
CSNK1E; DYNC1I2; ARF4; SSNA1; RP2; HAUS2; NPHP4; SETD6; DYNLRB1; NPHP1
BBSome-mediated cargo-targeting to cilium
LZTFL1; BBS7; BBS12; CCT4; SETD6; PROL1; SSTR3; TTC8; CCT8; TCP1
Basal cell carcinoma
SETD6; WNT9B; WNT8B; WNT9A; TP53; AXIN1; DVL3; Fzd4; WNT7A; WNT11
Cargo trafficking to the periciliary membrane
CNGA5; RP2; TCP1; LZTFL1; NPHP3; MKKS; ARF4; EXOC5; BBS2; CCT5
Class B/2 (Secretin family receptors)
RAMP3; EMR4; CRHB; PTHLHA; RAMP2; FZD10; SETD6; ADM2; CRHR2; GNB3B
GPCR ligand binding
CHRM5; GPRC6A; S1PR1; CALCB; SETD6; AGTR2; PROKR2; NMBB; ADCYAP1R1; PENKB
GPCRs, Other
GPR17; S1PR1; SSTR2; OR10A5; GPR143; GPR88; RRH; CELSR2; CELSR1; CELSR3

Protein Function

SETD6 has several biochemical functions, for example, G-protein coupled receptor activity, NOT Wnt-activated receptor activity, Wnt-protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SETD6 itself. We selected most functions SETD6 had, and list some proteins which have the same functions with SETD6. You can find most of the proteins on our site.
Function
Related Protein
Function G-protein coupled receptor activity
Related Protein OPRL1; CD97; GRM8; OR5H1; OR2F1; GPR151; OLFR5; TAAR13C; GPR1; GPR68
Function NOT Wnt-activated receptor activity
Related Protein SFRP4; SETD6; SFRP1; TSPAN12; SFRP1B; SFRP1A; SFRP2; FRZB; SMO; SZL
Function Wnt-protein binding
Related Protein FZD2; FZD8B; SFRP1A; FZD8A; FZD1; FZD3; LRP6; GPR177; FZD3B; ROR1
Function drug binding
Related Protein CHRNB4; CHRM3; PIGC; PYGM; IL2RA; GPR30; CYP2C9; CYP2D6; DRD3; FNTB
Function patched binding
Related Protein Shh; CCNB1; IHH; SETD6; SMO; BBS1; CAV1; PTCH1; DHH
Function protein binding
Related Protein ROCK1; LNX1; MED28; COL6A5; RFWD2; PACSIN2; PHAX; OPA1; IL24; ILK

Interacting Protein

SETD6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SETD6 here. Most of them are supplied by our site. Hope this information will be useful for your research of SETD6.
Ankrd1

SETD6 Related Articles

Yu, Y; Lasanajak, Y; et al. Human Milk Contains Novel Glycans That Are Potential Decoy Receptors for Neonatal Rotaviruses. MOLECULAR & CELLULAR PROTEOMICS 13:2944-2960(2014).
Back, JW; Frisch, C; et al. Selecting highly structure-specific antibodies using structured synthetic mimics of the cystine knot protein sclerostin. PROTEIN ENGINEERING DESIGN & SELECTION 25:251-259(2012).