SETD6 Protein, SET domain containing 6


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Official Full Name SET domain containing 6
Synonyms SETD6; SET domain containing 6; N-lysine methyltransferase SETD6; FLJ21148; SET domain-containing protein 6
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Insect Cell
    • Mammalian Cell
    • Tag :
    • GST
    • His
    • Myc
    • DDK
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human SETD6-1002H Recombinant Human SETD6 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human SETD6-200H Recombinant Human SETD6 protein, GST-tagged, Active Insect Cell GST
    Human SETD6-261H Recombinant Human SETD6 protein, GST-tagged E.coli GST
    Mouse SETD6-14983M Recombinant Mouse SETD6 Protein Mammalian Cell His
    Rat SETD6-5349R Recombinant Rat SETD6 Protein Mammalian Cell His
    Chicken SETD6-2277C Recombinant Chicken SETD6 Mammalian Cell His
    Zebrafish SETD6-10003Z Recombinant Zebrafish SETD6 Mammalian Cell His

    SETD6 involved in several pathways and played different roles in them. We selected most pathways SETD6 participated on our site, such as Activation of SMO, Assembly of the primary cilium, BBSome-mediated cargo-targeting to cilium, which may be useful for your reference. Also, other proteins which involved in the same pathway with SETD6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Activation of SMO EFCAB7; BOC; GAS8; EVC2; CDON; KIF3A; SETD6; EVC; ADRBK1; IQCE
    Assembly of the primary cilium IFT-20; RABL5; IFT74; CENPJ; CCT3; SSTR3; IFT46; CEP164; CEP72; FBF1
    BBSome-mediated cargo-targeting to cilium LZTFL1; TCP1; TTC8; CCT4; PROL1; BBS12; BBS5; SETD6; BBS9; BBS2
    Basal cell carcinoma WNT11; WNT16; FZD5; FZD8; SUFU; WNT7B; FZD2; TCF7L2; WNT10B; DVL1
    Cargo trafficking to the periciliary membrane BBS7; LZTFL1; ARF4; ARL13B; CCT3; BBS12; PROL1; SETD6; RP2; CCT8
    Class B/2 (Secretin family receptors) GCGB; CRHR1; GHRH; EMR3; ADCYAP1R1; PTH2; SCT; FZD10; PTH; CALCB
    GPCR ligand binding AMCF-II; CXCR7B; OXGR1A.1; KISS1; HEBP1; TAC1; LPAR1; GPR65; RAMP2; NPB
    GPCRs, Other VN1R1; VMN1R47; EMR3; OR10A5; GPR77; CELSR2; GPR61; GPR55; VMN1R41; GPR183

    SETD6 has several biochemical functions, for example, G-protein coupled receptor activity, NOT Wnt-activated receptor activity, Wnt-protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SETD6 itself. We selected most functions SETD6 had, and list some proteins which have the same functions with SETD6. You can find most of the proteins on our site.

    Function Related Protein
    G-protein coupled receptor activity TRHR2; GPR183B; VMN1R46; FZD2; TAAR1B; TAS2R139; TAS2R116; OXGR1; TAS2R137; APLNRB
    NOT Wnt-activated receptor activity SFRP1B; SMO; SETD6; SFRP1; SFRP4; SFRP2; FRZB; SFRP1A; TSPAN12; SZL
    Wnt-protein binding FZD7; WLS; FZD7B; SFRP1A; GPR177; ROR1; SFRP1B; FZD3B; LRP2A; FZD6
    patched binding DHH; CCNB1; SMO; SETD6; CAV1; PTCH1; IHH; BBS1; Shh
    protein binding MED28; CCT2; HSPA1L; SUV420H2; SMG5; RRAGA; MAZ; SLC4A1A; RTP4; DDX21

    SETD6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SETD6 here. Most of them are supplied by our site. Hope this information will be useful for your research of SETD6.


    Yu, Y; Lasanajak, Y; et al. Human Milk Contains Novel Glycans That Are Potential Decoy Receptors for Neonatal Rotaviruses. MOLECULAR & CELLULAR PROTEOMICS 13:2944-2960(2014).
    Back, JW; Frisch, C; et al. Selecting highly structure-specific antibodies using structured synthetic mimics of the cystine knot protein sclerostin. PROTEIN ENGINEERING DESIGN & SELECTION 25:251-259(2012).

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