Active Recombinant Human SETD6 protein, GST-tagged

• Cat.No.: SETD6-200H
• Product Overview: Recombinant Human SETD6 fused with GST tag at N-terminal was expressed in Insect cells.

Specification

• Species: Human
• Source: Insect Cells
• Tag: GST
• Description: SET domain-containing protein 6 (SETD6) is a mono-methyltransferase that has been shown to methylate RelA of NF-kappa-B complex and thus attenuate NF-kappa-B transcription factor activity. In addition, it monomethylates the histone H2A variant H2AZ which is required for the maintenance of embryonic stem cell self-renewal.
• Form: 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
• Bio-activity: 380 nmol/min/mg
• Molecular Mass: 75 kDa
• Purity: >80%
• Applications: Methyltransferase Assay
• Stability: 1 year at -70 centigrade from the date of shipment
• Storage: Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
• Concentration: 0.1μg/μl

Gene Information

• Gene Name: SETD6 SET domain containing 6 [ Homo sapiens ]
• Official Symbol: SETD6
• Synonyms: SETD6; SET domain containing 6; N-lysine methyltransferase SETD6; FLJ21148; SET domain-containing protein 6
• Gene ID: 79918
• mRNA Refseq: NM_001160305
• Protein Refseq: NP_001153777
• UniProt ID: Q8TBK2
• Chromosome Location: 16q21
• Function: NF-kappaB binding; methyltransferase activity; protein binding; protein-lysine N-methyltransferase activity; transferase activity