Recombinant Human SETD6 protein, GST-tagged

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Recombinant Human SETD6 protein, GST-tagged

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Cat.No. : SETD6-261H
Product Overview : Recombinant Human SETD6(1-473 aa) fused with GST tag at N-terminal was expressed in E. coli.
Description : SETD6 is a SET-domain containing protein lysine methyltransferase, catalyzing the mono-methylation of RelA (p65, NFkB3) at lysine 310. Methylation of RelA attenuates RelA-dependant transcriptional pathways, including inflammatory responses in primary immune cells. SETD6 is downregulated in a diseases of hyper inflammation.
Source : E. coli
Species : Human
Tag : GST
Form : 100 mM Tris pH 8.0, 10mM glutathione and 25% glycerol.
Molecular Mass : 72 kDa
Applications : Recombinant SETD6, human is useful for RelA/p65 methylation experiments, enzyme kinetics and inhibitor screening. Use of 2-5 µg SETD6 per reaction with 1 µg recombinant RelA as a substrate is recommended.
Storage : Stable for six months at -80 centigrade from date of receipt. For best results, aliquot and avoid multiple freeze/thaws.
Concentration : 2.2 µg/µl
Gene Name : SETD6 SET domain containing 6 [ Homo sapiens ]
Official Symbol : SETD6
Synonyms : SETD6; SET domain containing 6; N-lysine methyltransferase SETD6; FLJ21148; SET domain-containing protein 6;
Gene ID : 79918
mRNA Refseq : NM_001160305
Protein Refseq : NP_001153777
UniProt ID : Q8TBK2
Chromosome Location : 16q21

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