Recombinant Human SETD6 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: SETD6-3582H
• Product Overview: SETD6 MS Standard C13 and N15-labeled recombinant protein (NP_079136) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a methyltransferase that adds a methyl group to the histone H2AZ, which is involved in nuclear receptor-dependent transcription. The protein also interacts with several endogenous proteins which are involved in nuclear hormone receptor signaling. A related pseudogene is located on chromosome 2. Alternative splicing results in multiple transcript variants.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 50.6 kDa
• AA Sequence: MATQAKRPRVAGPVDGGDLDPVACF LSWCRRVGLELSPKVAVSRQGTVAG YGMVARESVQAGELLFVVPRAALLS QHTCSIGGLLERERVALQSQSGWVP LLLALLHELQAPASRWRPYFALWPE LGRLEHPMFWPEEERRCLLQGTGVP EAVEKDLANIRSEYQSIVLPFMEAH PDLFSLRVRSLELYHQLVALVMAYS FQEPLEEEEDEKEPNSPVMVPAADI LNHLANHNANLEYSANCLRMVATQP IPKGHEIFNTYGQMANWQLIHMYGF VEPYPDNTDDTADIQMVTVREAALQ GTKTEAERHLVYERWDFLCKLEMVG EEGAFVIGREEVLTEEELTTTLKVL CMPAEEFRELKDQDGGGDDKREEGS LTITNIPKLKASWRQLLQNSVLLTL QTYATDLKTDQGLLSNKEVYAKLSW REQQALQVRYGQKMILHQLLELTST RTRPLEQKLISEEDLAANDILDYKD DDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: SETD6 SET domain containing 6 [ Homo sapiens (human) ]
• Official Symbol: SETD6
• Synonyms: SETD6; SET domain containing 6; N-lysine methyltransferase SETD6; FLJ21148; SET domain-containing protein 6
• Gene ID: 79918
• mRNA Refseq: NM_024860
• Protein Refseq: NP_079136
• MIM: 616424
• UniProt ID: Q8TBK2