setmar
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  • Official Full Name
  • SET domain and mariner transposase fusion gene
  • Background
  • Histone-lysine N-methyltransferase SETMAR is an enzyme that in humans is encoded by the SETMAR gene.
  • Synonyms
  • SETMAR; SET domain and mariner transposase fusion gene; histone-lysine N-methyltransferase SETMAR; metnase; Histone lysine N methyltransferase SETMAR; Hsmar 1; Hsmar1; Mariner transposase Hsmar1; SET domain and mariner transposase fusion; SET domain and mariner transposase fusion gene containing protein; SET domain and mariner transposase fusion gene-containing protein; SETMR_HUMAN
Cat.#:SETMAR-1121HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human SETMAR Protein, MYC/DDK-tagged
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Cat.#:SETMAR-6966HTag:GST
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human SETMAR, GST-tagged
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Cat.#:SETMAR-93HTag:His
Source (Host):E.coliSpecies:Human
Product nameRecombinant Human SETMAR protein, His-tagged
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Cat.#:SETMAR-14988MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse SETMAR Protein
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Cat.#:SETMAR-5350RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat SETMAR Protein
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Cat.#:SETMAR-6335ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish SETMAR
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Cat.#:SETMAR-1588HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human SETMAR cell lysate
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Involved Pathway

SETMAR involved in several pathways and played different roles in them. We selected most pathways SETMAR participated on our site, such as Lysine degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with SETMAR were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Lysine degradation
ALDH7A1; PIPOX; GCDHB; ALDH3A2A; SETD1BA; SUV420H1; SETD2; TMLHE; AGXT2L2; KMT2A

Protein Function

SETMAR has several biochemical functions, for example, DNA topoisomerase binding, double-stranded DNA binding, endonuclease activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SETMAR itself. We selected most functions SETMAR had, and list some proteins which have the same functions with SETMAR. You can find most of the proteins on our site.
Function
Related Protein
Function DNA topoisomerase binding
Related Protein TOPORS; SETMAR
Function double-stranded DNA binding
Related Protein HLF; KIN; XRCC3; ERCC5; USF1; CRY1; PNKP; HNRNPDL; XRCC5; MCM10
Function endonuclease activity
Related Protein RNASE6; ENDOU2; EAR3; DNASE2A; RNASE2; EAR2; RNASE3; RNASE4; DIS3; SETMAR
Function histone methyltransferase activity (H3-K36 specific)
Related Protein SMYD2; SETD3; NSD1; SETD2; ASH1L; SETMAR; SMYD2A; SMYD2B
Function histone methyltransferase activity (H3-K4 specific)
Related Protein ASH1L; KMT2A; KMT2E; SETD3; MLL5; MLL1; WHSC1L1; WDR82; SETMAR; WBP7
Function protein binding
Related Protein EIF5A; NDEL1; MAPK9; COX8A; XPO1; FAM151B; RET; ZC3HAV1; ARF4; RPL10A
Function protein homodimerization activity
Related Protein IRAK3; NOG; NRF1; ASGR1; NTRK1; YARS2; BMPR1A; EVLA; Defa-rs7; ENG
Function single-stranded DNA binding
Related Protein TSN; FBXO18; SWSAP1; SETMAR; LONP1; NABP1; ERCC5; BRCA2; YBX1; MLH3
Function single-stranded DNA endodeoxyribonuclease activity
Related Protein MRE11A; RBBP8; ERCC4; SETMAR; DCLRE1C
Function structure-specific DNA binding
Related Protein TET1; SETMAR; ENDOV; TDG; EXO1
Function zinc ion binding
Related Protein GATA1A; BTR12; NBR1; MAN2C1; ZDHHC5; ENPEP; TTC3; ATRX; CBLB; RNF128A

Interacting Protein

SETMAR has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SETMAR here. Most of them are supplied by our site. Hope this information will be useful for your research of SETMAR.
H3F3C; Naa50; LEO1