sgcb
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  • Official Full Name
  • sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
  • Background
  • This gene encodes a member of the sarcoglycan family. Sarcoglycans are transmembrane components in the dystrophin-glycoprotein complex which help stabilize the muscle fiber membranes and link the muscle cytoskeleton to the extracellular matrix. Mutations in this gene have been associated with limb-girdle muscular dystrophy.
  • Synonyms
  • SGCB; sarcoglycan, beta (43kDa dystrophin-associated glycoprotein); LGMD2E, sarcoglycan, beta (43kD dystrophin associated glycoprotein); beta-sarcoglycan; A3b; SGC; 43DAG; beta-SG; 43 kDa dystrophin-associated glycoprotein; limb girdle muscular dystrophy
Cat.#:SGCB-75HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human SGCB, His-tagged
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Cat.#:SGCB-15029MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse SGCB Protein
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Cat.#:SGCB-2826CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken SGCB
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Cat.#:SGCB-3448ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish SGCB
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Cat.#:SGCB-1889HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human SGCB 293 Cell Lysate
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Involved Pathway

SGCB involved in several pathways and played different roles in them. We selected most pathways SGCB participated on our site, such as Hypertrophic cardiomyopathy (HCM), Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, which may be useful for your reference. Also, other proteins which involved in the same pathway with SGCB were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Hypertrophic cardiomyopathy (HCM)
CACNG1; TGFB2; CACNG7; ITGAV; CACNG3; TPM4; SLC8A1; MYL2; RYR2; LAMA2
Arrhythmogenic right ventricular cardiomyopathy (ARVC)
AASS; ITGA5; CTNNA1; ITGB4; CACNA2D4; CACNG1; ITGA2B; ITGA8; DSP; ACTN3
Dilated cardiomyopathy
CACNA2D3; ITGA10; ITGB5; CACNA2D1; PRKACA; ADRB1; CACNG7; ITGB4; CACNB1; PRKACB
Viral myocarditis
HLA-DRB4; ICAM1; ABL2; SGCD; HLA-DOB; HLA-G; HLA-DMA; CD86; MYH7; CAV1

Interacting Protein

SGCB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SGCB here. Most of them are supplied by our site. Hope this information will be useful for your research of SGCB.
TRIM63

SGCB Related Articles

Stehlikova, K; Skalova, D; et al. Autosomal recessive limb-girdle muscular dystrophies in the Czech Republic. BMC NEUROLOGY 14:-(2014).
Gibertini, S; Zanotti, S; et al. Fibrosis and inflammation are greater in muscles of beta-sarcoglycan-null mouse than mdx mouse. CELL AND TISSUE RESEARCH 356:427-443(2014).