shox2
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  • Official Full Name
  • short stature homeobox 2
  • Background
  • This gene is a member of the homeobox family of genes that encode proteins containing a 60-amino acid residue motif that represents a DNA binding domain. Homeobox genes have been characterized extensively as transcriptional regulators involved in pattern formation in both invertebrate and vertebrate species. Several human genetic disorders are caused by aberrations in human homeobox genes. This locus represents a pseudoautosomal homeobox gene that is thought to be responsible for idiopathic short stature, and it is implicated in the short stature phenotype of Turner syndrome patients. This gene is considered to be a candidate gene for Cornelia de Lange syndrome. Alternative splicing results in multiple transcript variants.
  • Synonyms
  • SHOX2; short stature homeobox 2; short stature homeobox protein 2; OG12; OG12X; SHOT; Homeobox protein Og12X; OG 12; OG 12X; OGI 2X; OGI2X; Paired related homeobox protein SHOT; Paired-related homeobox protein SHOT; Short stature homeobox homolog; SHOX 2; SHOX homologous gene on chromosome 3; SHOX2_HUMAN; OTTHUMP00000213397; OTTHUMP00000213398; OTTHUMP00000213399; OTTHUMP00000245277
Cat.#:SHOX2-2665HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human SHOX2, His-tagged
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Cat.#:SHOX2-31358THTag:N/A
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human SHOX2
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Cat.#:SHOX2-15111MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse SHOX2 Protein
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Cat.#:SHOX2-5395RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat SHOX2 Protein
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Cat.#:SHOX2-11413ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish SHOX2
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Cat.#:SHOX2-1604HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human SHOX2 cell lysate
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Protein Function

SHOX2 has several biochemical functions, for example, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SHOX2 itself. We selected most functions SHOX2 had, and list some proteins which have the same functions with SHOX2. You can find most of the proteins on our site.
Function
Related Protein
Function sequence-specific DNA binding
Related Protein HOXD12; IRX2A; HOXA1; FOXP1B; TBX3; FOXS1; HOXB1A; FOXP3; ISL1L; MAF

Interacting Protein

SHOX2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SHOX2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SHOX2.
CDK4