slc19a2
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  • Official Full Name
  • solute carrier family 19 (thiamine transporter), member 2
  • Background
  • This gene encodes the thiamin transporter protein. Mutations in this gene cause thiamin-responsive megaloblastic anemia syndrome (TRMA), which is an autosomal recessive disorder characterized by diabetes mellitus, megaloblastic anemia and sensorineural deafness.
  • Synonyms
  • SLC19A2; solute carrier family 19 (thiamine transporter), member 2; TRMA; thiamine transporter 1; THTR1; S19A2_HUMAN; Solute carrier family 19 member 2; TC1; Thiamine carrier 1; THT1; ThTr 1; ThTr-1; OTTHUMP00000033497; OTTHUMP00000033498; OTTHUMP00000033499; high affinity thiamine transporter; reduced folate carrier protein (RFC) like
Cat.#:SLC19A2-4227RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey SLC19A2 Protein, His-tagged
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Cat.#:SLC19A2-1617HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human SLC19A2 cell lysate
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Involved Pathway

SLC19A2 involved in several pathways and played different roles in them. We selected most pathways SLC19A2 participated on our site, such as Metabolism, Metabolism of vitamins and cofactors, Metabolism of water-soluble vitamins and cofactors, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC19A2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Metabolism
CDO1; OMD; CERS5; PLIN2; CYP4T8; Gpc2; SLC25A10; GPHN; APOA4A; CPNE1
Metabolism of vitamins and cofactors
LOC100686744; SLC46A1; SLC5A6B; SLC25A32B; MOCOS; CYB5R3; CTRB1; SLC19A2; PDZD11; ELA2L
Metabolism of water-soluble vitamins and cofactors
SLC25A32A; CD320; GSTO2; KCNG4; ELA2L; ELA2; SLC23A2; GPHN; SLC52A3; PDZD11
Vitamin B1 (thiamin) metabolism
SLC19A2
Vitamin digestion and absorption
SLC46A1; SLC19A2; SLC23A1; BTD; SLC52A3; FOLH1; CUBN; TCN2; LRAT; SCARB1

Protein Function

SLC19A2 has several biochemical functions, for example, folic acid transporter activity, protein binding, thiamine transmembrane transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC19A2 itself. We selected most functions SLC19A2 had, and list some proteins which have the same functions with SLC19A2. You can find most of the proteins on our site.
Function
Related Protein
Function folic acid transporter activity
Related Protein SLC19A2; DAAM2; SLC25A32; FOLR2; SLC46A1; SLC19A1; FOLR1
Function protein binding
Related Protein S100P; ACTR6; DUSP1; ERCC4; RASSF4; HIST1H2AG; HJURP; SPATA22; KIF27; CKS1B
Function thiamine transmembrane transporter activity
Related Protein SLC19A2
Function thiamine uptake transmembrane transporter activity
Related Protein SLC19A3B; SLC19A2; C2orf83; SLC19A3

Interacting Protein

SLC19A2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC19A2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC19A2.
CERS2